Phenylbute Paste (60ml) | On Sale | EntirelyPets Rx
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Phenylbute Paste (60ml)

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Recurring Saings in EprxAUTOSHIP & SAVE[Details]
Recurring Saings in EprxAUTOSHIP & SAVE[Details]
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Bute (Phenylbute) Paste is for the relief of inflammatory conditions associated with the musculoskeletal system in horses. Phenylzone Paste is a synthetic, nonhormonal, anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties.

Key Benefits

  • Relieves pain and inflammation
  • Particularly good for osteoarthritis
  • Reduces fever
  • Inexpensive
  • Paste comes in a tasty apple flavor

How It Works

Phenylbutazone is a non-steroidal anti-inflammatory drug (NSAID) which through its anti-inflammatory action can relieve pain, reduce inflammation and reduce fever.


For the relief of inflammatory conditions associated with the musculoskeletal system in horses.


Orally - 1 to 2 g of phenylbutazone per 500 lb. of body weight daily. Do not exceed 4 g daily.

Guidelines to Successful Therapy: Use a relatively high dose for the first 48 hours, then reduce gradually to a maintenance dose. Maintain lowest dose capable of producing desired clinical response. Response to Phenylbutazone Paste therapy is prompt, usually occurring within 24 hours. If no significant clinical effect is evident after five days, re-evaluate diagnosis and therapeutic approach.

When administering Phenylbutazone Paste, the oral cavity should be empty. Deposit paste on back of tongue by depressing plunger that has been previously set to deliver the correct dose. Many chronic conditions will respond to Phenylbutazone Paste therapy, but discontinuance of treatment may result in recurrence of symptoms.


Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian.


Use with caution in patients who have a history of drug allergy.


Not for use in horses intended for food.


Stop medication at the first sign of gastrointestinal upset, jaundice or blood dyscrasia. Authenticated cases of agranulocytosis associated with the drug have occurred in man; fatal reactions, although rare, have been reported in dogs after long-term therapy. To guard against this possibility, conduct routine blood counts at weekly intervals during the early phase of therapy and at intervals of two weeks thereafter. Any significant fall in the total white blood cell count, relative decrease in granulocytes, or black or tarry stools should be regarded as a signal for immediate cessation of therapy and institution of appropriate counter-measures.In the treatment of inflammatory conditions associated with infections, specific anti-infective therapy is required.


Store at 15°C - 30°C (59°-86°F)


Phenylbutazone is a prescription medication FDA approved for use in horses. It is available as 1 gram (1000 mg) scored tablets, 100 ml injectable solution, and 60 ml oral paste. The usual dose in horses is 2 to 4 Grams (2,000 to 4,000 mg) per 1000 pounds every 24 hours, which is 2-4 tablets, 10-20 ml, or 2-4 markings on the syringe plunger. Phenylbutazone tablets should be given with food. Phenylbutazone injectable solution should be administered intravenously. The injectable solution does not include a syringe. Phenylbutazone Oral Paste should be administered by the mouth. Phenylbutazone should not be given to animals who are dehydrated or have stomach ulcers, anemia or bleeding disorders, or liver, kidney or heart disease.
Phenylbutazone is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with fractures, arthritis and painful injuries to the limbs and joints. Phenylbutazone may be used for purposes other than those listed in this medication guide.
Tell your veterinarian if your horse has ever had an allergic reaction to phenylbutazone or any other NSAID. Tell your veterinarian if your horse has any liver, kidney or heart disease. Tell your veterinarian if your horse is pregnant or lactating. Talk to your veterinarian about the appropriate syringe to use with Phenylbutazone Injectable Solution.
Give this medication exactly as directed by your veterinarian. If you do not understand the directions, ask your pharmacist or veterinarian to explain them to you. Tablets should be given with food. Phenylbutazone injectable solution should be administered intravenously. Store this medication at room temperature. Keep out of the reach of children and pets.
Give the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and give the next one as directed. Do not give a double dose of the medication.
In the event of overdose, contact your veterinarian or veterinary emergency room. Symptoms of overdose may include decreased urine production and blood in the urine, jaundice (yellowing of the skin, gums and eyes), pale gums, weakness, and ulcers.
Do not use phenylbutazone in animals allergic to it or other NSAIDs. Do not use in pregnant or lactating mares. Do not give phenylbutazone with other NSAIDs, corticosteroids, or other ulcer causing medications.
Side effects that may occur when using phenylbutazone may include ulcers, kidney damage, bloody stool, decreased white blood cells and platelets as well as an allergic reaction (facial swelling, hives, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, coma). Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your horse.
Use caution when giving phenylbutazone with phenytoin, warfarin, sulfonamides, glipizide, digoxin, barbiturates, rifampin, chlorpheniramine or diphenhydramine. Talk to your veterinarian or pharmacist before using phenylbutazone with any prescription or over the counter medications, including vitamins, minerals and herbal supplements.
Your pharmacist has additional information about phenylbutazone written for health professionals that you may read.


Review Summary
2 Reviews
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100% Recommend this product (2 of 2 responses)
By Donna
easy to use
March 24, 2021
Easy to use just like any oral paste. Very handy to have on hand for minor injuries that come up suddenly.
  • easy to administer
  • large tube for small hands
By Kathy
Winlock, WA
Paste - the way to go!
November 13, 2020
So much easier to administer in the paste form.

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