Enroflox™ (enrofloxacin) Injection for Dogs 2.27% (50 ml) | On Sale | EntirelyPets Rx
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Enroflox (enrofloxacin) Injection for Dogs 2.27% (50 ml) (Manufacturer may vary)

Item# ENRO2438
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Enroflox a fluoroquinolone designed for the management of bacterial diseases, with broad-spectrum activity against both gram-negative and gram-positive bacteria including those causing dermal, respiratory and urinary tract infections. Each mL of injectable solution contains 22.7 mg of enrofloxacin. Enroflox Injection is available for dogs only.

Key Benefits

  • Same active ingredient and dosing regimen as Baytril Injectable Solution 2.27%
  • Concentration-dependent and bactericidal
  • Kills a broad range of Gram (+) and Gram (-) Bacteria
  • Significant savings versus Baytril Injectable Solution 2.27
  • Available in 20 mL, 50 mL and economical 100 mL vials to fit any practice


Enroflox (brand of enrofloxacin) Injectable Solution is indicated for the management of diseases in dogs associated with bacteria susceptible to enrofloxacin.


View Enroflox Drug Facts Sheet.

Enroflox Injection for Dogs may be used as the initial dose at 2.5 mg/kg. It should be administered intramuscularly (IM) as a single dose, followed by initiation of enrofloxacin tablet therapy.

Enroflox Injection for Dogs may be administered as follows:

Weight Of Animal Enroflox Injection for Dogs* 2.5 mg/kg
9.1 kg (20 lb) 1.00 mL
27.2 kg (60 lb) 3.00 mL

*The initial Enroflox Injection for Dogs administration should be followed 12 hours later by initiation of enrofloxacin tablet therapy.

The lower limit of the dose range was based on efficacy studies in dogs where enrofloxacin was administered at 2.5 mg/kg twice daily. Target animal safety and toxicology studies were used to establish the upper limit of the dose range and treatment duration.


Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian.


Quinolone-class drugs should be used with caution in animals with known or suspected Central Nervous System (CNS) disorders. In such animals, quinolones have, in rare instances, been associated with CNS stimulation which may lead to convulsive seizures.

Quinolone-class drugs have been associated with cartilage erosions in weight-bearing joints and other forms of arthropathy in immature animals of various species.

The use of fluoroquinolones in cats has been reported to adversely affect the retina. Such products should be used with caution in cats.


For use in animals only. The use of this product in cats may result in Retinal Toxicity. Keep out of reach of children.

Avoid contact with eyes. In case of contact, immediately flush eyes with copious amounts of water for 15 minutes. In case of dermal contact, wash skin with soap and water. Consult a physician if irritation persists following ocular or dermal exposure. Individuals with a history of hypersensitivity to quinolones should avoid this product. In humans, there is a risk of user photosensitization within a few hours after excessive exposure to quinolones. If excessive accidental exposure occurs, avoid direct sunlight.For customer service, to obtain a copy of the Material Safety Data Sheet (MSDS) or to report adverse reactions call Norbrook at 1-866-591-5777.


Enrofloxacin is contraindicated in dogs known to be hypersensitive to quinolones.

Based on the studies discussed under the section on Animal Safety Summary, the use of enrofloxacin is contraindicated in small and medium breeds of dogs during the rapid growth phase (between 2 and 8 months of age). The safe use of enrofloxacin has not been established in large and giant breeds during the rapid growth phase. Large breeds may be in this phase for up to one year of age and the giant breeds for up to 18 months. In clinical field trials utilizing a daily oral dose of 5.0 mg/kg, there were no reports of lameness or joint problems in any breed. However, controlled studies with histological examination of the articular cartilage have not been conducted in the large or giant breeds.


Store at 59°-77°F (15°-25°C). Excursions permitted up to 86°F (30°C). Brief exposure to temperature up to 104°F (40°C) may be tolerated provided the mean kinetic temperature does not exceed 77°F (25°C); however, such exposure should be minimized. Protect from direct sunlight. Do not freeze

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