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Chorulon is a freeze-dried preparation of chorionic gonadotropin (human Chorionic Gonadotropin or hCG) for intramuscular administration after reconstitution. When reconstituted with the accompanying sterile diluent, each 10 mL vial contains 10,000 I.U. chorionic gonadotropin (equivalent to 10,000 USP Units chorionic gonadotropin) and 10 mg mannitol, with mono- and disodium phosphate to adjust the pH of the solution.
Finfish: Chorulon is indicated for use as an aid in improving spawning function in male and female brood finfish.
To reconstitute, transfer the contents of one vial of sterile diluent into one vial of freeze-dried powder. The resulting 10 mL of CHORULON contains 10,000 I.U. chorionic gonadotropin.
COWS: The contents of one vial (10 mL) of reconstituted CHORULON should be administered as a single deep intramuscular injection. Dosage may be repeated in 14 days if the animal's behavior or rectal examination of the ovaries indicates the necessity for retreatment.
FINFISH: CHORULON should be administered via intramuscular injection just ventral to the dorsal fin for one (1) to three (3) injections. Any single injection should be administered, depending on the fish species, at a dose of 50 to 510 I.U./lb body weight (bw) for males and 67 to 1816 I.U./lb bw for females. Depending on body weight and dose administered, it may be necessary to divide the dose among two or more injection sites to avoid injecting a large volume at a single site.
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Chorionic gonadotropin is a protein. In the unlikely event of an anaphylactic reaction, epinephrine should be administered. The administration of an antihistamine may also be indicated.
No withdrawal period is required for cows or brood finfish treated according to label directions. The total dose administered (all injections combined) should not exceed 25,000 I.U. (25 mL) per fish in fish intended for human consumption.
Store at or below room temperature, 77°F (25°C). Keep out of reach of children. Once reconstituted, CHORULON should be used immediately. Unused solution should be disposed of properly and not stored for future use.