View Cerenia package insert.
Dosage & Administration
Cerenia exactly as directed by your veterinarian. If you do not understand these directions, ask your pharmacist or veterinarian to explain them to you. For prevention of motion sickness, Cerenia should be given 2 hours before traveling, but you should not feed your pet for at least 1 hour before giving Cerenia. Blood tests or other medical evaluations may be required by your veterinarian to monitor your pet.
Quick Tips
- For prevention of acute vomiting, Cerenia should be given orally at a minimum dose of 2 mg/kg body weight once daily for up to 5 consecutive days.
- For prevention of vomiting due to motion sickness, Cerenia should be given orally at a minimum dose of 8 mg/kg body weight once daily for up to 2 consecutive days. Dogs should be fasted 1 hour prior to administration of tablets. Administer 2 hours before travel.
- Use only as directed on package or instructions given by your veterinarian.
Dosage Tables
Acute Vomiting Prevention
| Weight (lbs.) | Dosage |
| 2.2-8.8 | 1/2 tablet (16 mg) |
| 8.9-17.6 | 1 tablet (16 mg) |
| 17.7-26.4 | 1 tablet (24 mg) |
| 26.5-52.8 | 2 tablets (24 mg) |
| 52.9-66.0 | 1 tablet (60 mg) |
| 66.1-132.0 | 2 tablets (60 mg) |
Vomiting Prevention Due to Motion Sickness
| Weight (lbs.) | Dosage |
| 2.2 | 1/2 tablet (16 mg) |
| 2.3-3.3 | 1/2 tablet (24 mg) |
| 3.4-4.4 | 1 tablet (16 mg) |
| 4.5-6.6 | 1 tablet (24 mg) |
| 6.7-8.8 | 2 tablets (16 mg) |
| 8.9-13.2 | 2 tablets (24 mg) |
| 13.3-16.5 | 1 tablet (60 mg) |
| 16.6-22.0 | 1/2 tablet (160 mg) |
| 22.1-33.0 | 2 tablets (60 mg) |
| 33.1-44.0 | 1 tablet (160 mg) |
| 44.1-66.0 | 1 1/2 tablets (160 mg) |
| 66.1-88.0 | 2 tablets (160 mg) |
| 88.1-132.0 | 3 tablets (160 mg) |
Storage
Store Cerenia at controlled room temperature (68° -77° F). Keep this medication out of the reach of children and other pets.
Warnings
Not for use in humans. Keep out of the reach of children. In case of accidental ingestion, seek medical advice. Topical exposure may elicit localized allergic skin reactions in some individuals. Repeated or prolonged exposure may lead to skin sensitization. Wash hands with soap and water after administering drug. Cerenia is also an ocular irritant. In case of accidental eye exposure, flush with water for 15 minutes and seek medical attention.
In puppies younger than 11 weeks of age, histological evidence of bone marrow hypocellularity was observed at higher frequency and greater severity in puppies treated with Cerenia compared to control puppies. In puppies 16 weeks and older, bone marrow hypocellularity was not observed.
Precautions
The safe use of Cerenia Tablets has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens. The safe use of Cerenia Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins.
Use with caution in patients with hepatic dysfunction because Cerenia Injectable Solution is metabolized by CYP3A, CYP2D15 (dogs) and CYP1A (cats) enzymes. The influence of concomitant drugs that may inhibit the metabolism of Cerenia Injectable Solution has not been evaluated. Cerenia Injectable Solution is highly protein bound. Use with caution with other medications that are highly protein bound. The concomitant use of Cerenia Injectable Solution with other protein bound drugs has not been studied in dogs or cats. Commonly used protein bound drugs include NSAIDs, cardiac, anticonvulsant, and behavioral medications. Drug compatibility should be monitored in patients requiring adjunctive therapy.
Cerenia Tablets causes dose related decreases in appetite and body weight. To maximize therapeutic potential of Cerenia Tablets, the underlying cause of vomiting should be identified and addressed in dogs receiving Cerenia Tablets.
The safe use of Cerenia Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
Possible Side Effects
If any of the following serious side effects occur, stop giving Cerenia and seek emergency veterinary medical attention: an allergic reaction (difficulty breathing, swelling of the lips, tongue, or face; hives); sudden onset of diarrhea; vomiting; shock; seizures; coma. Other less serious side effects may occur. If any of the following side effects occur, continue to give Cerenia and talk to your veterinarian: drooling, lethargy, drowsiness. Side effects other than those listed in this guide may occur. Talk to your veterinarian about any side effect that seems unusual or that is especially bothersome to your pet.
