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Bravecto for Dogs - 9.9-22 lbs (4 Chews) Video
Bravecto for Dogs - 9.9-22 lbs (4 Chews) Video

Bravecto for Dogs - 9.9-22 lbs (4 Chews)

Item# IWM0526656
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  • Description
  • Ingredients
  • Directions
  • FAQ
  • Reviews

Description

Bravecto Chews is the first oral chew for dogs to provide up to 12 weeks of protection against fleas and ticks. One chew provides broad-spectrum and long-lasting protection that starts to kill fleas within 2 hours and controls 4 tick species: black-legged tick (a.k.a. deer tick), American dog tick, brown dog tick, and lone star tick. Bravecto Chews eliminates current flea infestations and prevents new ones from developing for 12 weeks. With one chew, Bravecto Chews is easier to give and less to worry about for you! Bravecto Chews requires a prescription from your veterinarian.

Key Benefits

  • With one dose, Bravecto Chews resets the clock on flea and tick protection by providing effective prevention and treatment for both fleas and ticks for up to 12 weeks.
  • Close to a full year of protection with only 4 doses. No more monthly dosing!
  • No potential for messy application issues and no need to isolate from children or other pets after treatment
  • Fewer doses mean fewer chances to miss a dose decreasing the likelihood of having gaps in protection
  • Dogs love the taste!

How It Works

After giving your dog Bravecto Chews, the medication quickly reaches tissue fluids under your dog's skin. When fleas and ticks feed on your dog, they ingest Bravecto and die. Bravecto Chews kills fleas, prevents flea infestations and kills ticks (black-legged tick (a.k.a. deer tick), American dog tick, and brown dog tick) for 12 weeks. Bravecto Chews also kills lone star ticks for 8 weeks.

Indications

Bravecto kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (blacklegged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)] for 12 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater.

Bravecto is also indicated for the treatment and control of Amblyomma americanum (lone star tick) infestations for 8 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater.

Bravecto Chews is a registered trademark of Intervet Inc., d/b/a Merck Animal Health, a subsidiary of Merck & Co. Inc.

Ingredients

Bravecto Chews 4.4-9.9 lbs:
Active Ingredient (per tablet) Amount
Fluralaner 112.5 mg
Bravecto Chews >9.9-22.0 lbs:
Active Ingredient (per tablet) Amount
Fluralaner 250 mg
Bravecto Chews >22.0-44.0 lbs:
Active Ingredient (per tablet) Amount
Fluralaner 500 mg
Bravecto Chews >44.0-88.0 lbs:
Active Ingredient (per tablet) Amount
Fluralaner 1000 mg
Bravecto Chews >88.0-123.0 lbs:
Active Ingredient (per tablet) Amount
Fluralaner 1,400 mg

Directions

View Bravecto Chews Drug Facts Sheet.

Bravecto should be administered orally as a single dose every 12 weeks according to the Dosage Schedulebelow to provide a minimum dose of 11.4 mg/lb (25 mg/kg) body weight.

Bravecto may be administered every 8 weeks in case of potential exposure to Amblyomma americanum ticks (see Effectiveness).

Bravecto should be administered with food.

Dosage Schedule
Body Weight Ranges (lb) Fluralaner Content (mg) Chews Administered
4.4 - 9.9 112.5 1 (Yellow)
>9.9 - 22.0 250 1 (Orange)
>22.0 - 44.0 500 1 (Green)
>44.0 - 88.0 1000 1 (Blue)
>88.0 - 123.0* 1400 1 (Purple)

*Dogs over 123.0 lb should be administered the appropriate combination of chews

The potential risks ticks pose to pets can be stressful to pet owners wanting to ensure their pet receives effective coverage. Bravecto kills 4 different species of ticks commonly found on dogs and 2 species found on cats to protect your pet for 12 weeks.*5-7

PROTECT YOUR PET AGAINST THESE TICK SPECIES5-7

Contraindications:

There are no known contraindications for the use of the product.

Warnings:

Not for human use. Keep this and all drugs out of the reach of children. Keep the product in the original packaging until use, in order to prevent children from getting direct access to the product.

Do not eat, drink or smoke while handling the product. Wash hands thoroughly with soap and water immediately after use of the product.

Precautions:

Bravecto has not been shown to be effective for 12-weeks duration in puppies less than 6 months of age. Bravecto is not effective against Amblyomma americanum ticks beyond 8 weeks after dosing (see Effectiveness).

Adverse Reactions:

In a well-controlled U.S. field study, which included 294 dogs (224 dogs were administered Bravecto every 12 weeks and 70 dogs were administered an oral active control every 4 weeks and were provided with a tick collar); there were no serious adverse reactions. All potential adverse reactions were recorded in dogs treated with Bravecto over a 182-day period and in dogs treated with the active control over an 84-day period. The most frequently reported adverse reaction in dogs in the Bravecto and active control groups was vomiting.

Percentage of Dogs with Adverse Reactions in the Field Study
Adverse Reaction (AR) Bravecto Group: Percentage of Dogs with the AR During the 182-Day Study (n=224 dogs) Active Control Group: Percentage of Dogs with the AR During the 84-Day Study (n=70 dogs)
Vomiting 7.1 14.3
Decreased Appetite 6.7 0.0
Diarrhea 4.9 2.9
Lethargy 5.4 7.1
Polydipsia 1.8 4.3
Flatulence 1.3 0.0

In a well-controlled laboratory dose confirmation study, one dog developed edema and hyperemia of the upper lips within one hour of receiving Bravecto. The edema improved progressively through the day and had resolved without medical intervention by the next morning.

For technical assistance or to report a suspected adverse drug reaction, contact Merck Animal Health at 1-800-224-5318. Additional information can be found at www.bravecto.com. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth.

Clinical Pharmacology:

Peak fluralaner concentrations are achieved between 2 hours and 3 days following oral administration, and the elimination half-life ranges between 9.3 to 16.2 days. Quantifiable drug concentrations can be measured (lower than necessary for effectiveness) through 112 days. Due to reduced drug bioavailability in the fasted state, fluralaner should be administered with food.

Mode of Action:

Fluralaner is for systemic use and belongs to the class of isoxazoline-substituted benzamide derivatives. Fluralaner is an inhibitor of the arthropod nervous system. The mode of action of fluralaner is the antagonism of the ligand-gated chloride channels (gamma-aminobutyric acid (GABA)-receptor and glutamate-receptor).

Effectiveness:

Bravecto began to kill fleas within two hours after administration in a well-controlled laboratory study. In a European laboratory study, Bravecto killed fleas and Ixodes ricinus ticks and reduced the numbers of live fleas and Ixodes ricinus ticks on dogs by >98% within 12 hours for 12 weeks. In a well-controlled laboratory study, Bravecto demonstrated 100% effectiveness against adult fleas 48 hours post-infestation for 12 weeks. In well-controlled laboratory studies, Bravecto demonstrated ≥93% effectiveness against Dermacentor variabilis, Ixodes scapularis and Rhipicephalus sanguineus ticks 48 hours post-infestation for 12 weeks. Bravecto demonstrated ≥90% effectiveness against Amblyomma americanum 72 hours post-infestation for 8 weeks, but failed to demonstrate ≥90% effectiveness beyond 8 weeks.

In a well-controlled U.S. field study, a single dose of Bravecto reduced fleas by ≥99.7% for 12 weeks. Dogs with signs of flea allergy dermatitis showed improvement in erythema, alopecia, papules, scales, crusts, and excoriation as a direct result of eliminating flea infestations.

Palatability: In a well-controlled U.S. field study, which included 559 doses administered to 224 dogs, 80.7% of dogs voluntarily consumed Bravecto within 5 minutes, an additional 12.5% voluntarily consumed Bravecto within 5 minutes when offered with food, and 6.8% refused the dose or required forced administration.

Animal Safety:

Margin of Safety Study: In a margin of safety study, Bravecto was administered orally to 8 - to 9-week-old puppies at 1, 3, and 5X the maximum label dose of 56 mg/kg at three, 8-week intervals. The dogs in the control group (0X) were untreated.

There were no clinically-relevant, treatment-related effects on physical examinations, body weights, food consumption, clinical pathology (hematology, clinical chemistries, coagulation tests, and urinalysis), gross pathology, histopathology, or organ weights. Diarrhea, mucoid and bloody feces were the most common observations in this study, occurring at a similar incidence in the treated and control groups. Five of the twelve treated dogs that experienced one or more of these signs did so within 6 hours of the first dosing. One dog in the 3X treatment group was observed to be dull, inappetant, with evidence of bloody diarrhea, vomiting, and weight loss beginning five days after the first treatment. One dog in the 1X treatment group vomited food 4 hours following the first treatment.

Reproductive Safety Study: Bravecto was administered orally to intact, reproductively-sound male and female Beagles at a dose of up to 168 mg/kg (equivalent to 3X the maximum label dose) on three to four occasions at 8-week intervals. The dogs in the control group (0X) were untreated.

There were no clinically-relevant, treatment-related effects on the body weights, food consumption, reproductive performance, semen analysis, litter data, gross necropsy (adult dogs) or histopathology findings (adult dogs and puppies). One adult treated dog suffered a seizure during the course of the study (46 days after the second treatment). Abnormal salivation was observed on 17 occasions: in six treated dogs (11 occasions) after dosing and four control dogs (6 occasions).

The following abnormalities were noted in 7 pups from 2 of the 10 dams in only the treated group during gross necropsy examination: limb deformity (4 pups), enlarged heart (2 pups), enlarged spleen (3 pups), and cleft palate (2 pups). During veterinary examination at Week 7, two pups from the control group had inguinal testicles, and two and four pups from the treated group had inguinal and cryptorchid testicles, respectively. No undescended testicles were observed at the time of necropsy (days 50 to 71).

In a well-controlled field study Bravecto was used concurrently with other medications, such as vaccines, anthelmintics, antibiotics, and steroids. No adverse reactions were observed from the concurrent use of Bravecto with other medications.

Storage

Do not store above 86°F (30°C).

FAQ

Yes. Bravecto Chew and Bravecto Topical Solution for Dogs is vet recommended for puppies and dogs 6 months of age or older who weigh at least 4.4 lb.1,2 Bravecto Topical Solution for Cats is vet recommended for kittens and cats 6 months of age or older who weigh at least 2.6 lb.3

Bravecto has a wide margin of safety in dogs who weigh at least 4.4 lb. and cats who weigh at least 2.6 lb. It is also approved for puppies and kittens aged 6 months or older.1-3

Bravecto Chew is approved for use in breeding, pregnant, and lactating dogs.1,4

Bravecto is the only flea and tick treatment that lasts 12 weeks* with 1 convenient chew or topical dose.1-3 Compared to any monthly treatment, your pet is protected nearly 3 times longer with Bravecto.

The long-lasting protection of Bravecto effectively eliminates flea infestations on pets with just 1 dose.7,8 Plus, Bravecto kills ticks faster-killing 100% of attached ticks in 12 hours. Other treatments can take over 48 hours.9

Yes.1-3, 9
After you give your pet Bravecto, it quickly reaches tissue fluids just under your dog's or cat's skin. When fleas and ticks feed, they ingest Bravecto and die.

Bravecto Chew starts killing fleas (Ctenocephalides felis) within 2 hours, and kills ticks (Ixodes ricinus) within 12 hours.*1 Bravecto Chew kills fleas, prevents flea infestations, and kills ticks (black-legged tick, American dog tick, and brown dog tick) for 12 weeks. Bravecto Chew also kills lone star ticks for 8 weeks.1

Bravecto Topical Solution for Dogs reduces fleas by ≥99% and 100% within 24 and 48 hours, respectively, post-infestation for 12 weeks.* It kills ≥93.3% of black-legged ticks, American dog ticks and brown dog ticks after 48 hours for 12 weeks* and kills ≥90% lone star ticks 72 hours post-infestation for 8 weeks.2

Bravecto Topical Solution for Cats kills 100% of fleas within 8 hours. Applied to the base of the skull, your cat will have full-body protection for 12 weeks*-killing fleas, preventing flea infestations, and killing black-legged ticks. Bravecto Topical Solution for Cats also kills American dog ticks for 8 weeks.3

There are no problems reported in field trials in dogs and cats that received Bravecto alongside other commonly used medicines.1-3, 12 However, your veterinarian is your pet's healthcare expert, so it is always best to discuss all of your pet's treatments with them, whether prescription or over-the-counter supplements.
In a US field study where dogs were treated at home, over 93% of dogs ate the chew voluntarily-either by itself or with food.1
Bravecto Chew should be given with food. If a chew is broken or crumbles, make sure your dog still receives the whole dose.
No.
No. Even immediate bathing, shampooing, or swimming won't affect how well Bravecto Chew works because it's not a topical treatment. Coat length and grooming or brushing also have no impact on how well it works.
Yes. Bravecto is approved for use in breeding, pregnant, and lactating dogs.1,4
In a well-controlled laboratory study, Bravecto was shown to be safe in collies known to be MDR-1 gene deficient. Collies with the defect were administered 3 times the deliverable dose and had no adverse events.11
It is always best to discuss your pet's medical treatment with your veterinarian. However, Bravecto has a high margin of safety. In safety studies, Bravecto was tested in healthy dogs and puppies at up to 5 times the recommended dose at 8-week intervals for 3 treatments.1 Therefore, no adverse effects are expected if dogs are inadvertently treated twice with the recommended dose within 12 weeks, but please contact your veterinarian.

If vomiting occurs, check with your vet to decide whether to redose or not; however, if an otherwise healthy dog vomits within 3 hours of receiving Bravecto , it is recommended that the dog be redosed. To help ensure that the dog does not vomit again, it is suggested to wait 24 hours until redosing.

If 4 or more hours have passed before the vomiting occurs, it is likely that the medication has been absorbed and the dog is protected. If the vomiting repeats again, DO NOT give a third chew, and call your veterinarian.

If you suspect that a side effect has taken place as a result of giving the dog Bravecto, please report it to Merck Technical Services at 1-800-224-5318, and follow any advice that they provide.1

Reviews

Review Summary
4.7
266 Reviews
5
75% (199)
4
22% (59)
3
2% (4)
2
1% (2)
1
1% (2)
98% Recommend this product (261 of 266 responses)
By FRED
Tennessee
Great for Dogs over 60 Pounds
September 6, 2021
We have ordered these for our two (2) dogs over 60 pounds each. The dogs take these with ease and digests well.
By Andrea
Oklahoma
Bravecto
September 2, 2021
This stuff really works. Even if your dog has invited a flea into your house, once it bites your dog, it dies. Win win.

I love this stuff..
By Bliss
Kerrville, TX
Worked once but not the 2nd time
August 18, 2021
I used this on my small dogs and it worked for 3 months on the first dose, but only a month and half on the 2nd dose. The fleas out here adapt quickly. 😕
By Colleen M.
Napa CA 94559
Flea medication
August 8, 2021
I have used Bravecto for dogs88-123 lbs. in the past. Is effective but does not kill fleas instantly when they are on my dog. May take 2 hours.
By Kristi
Sinking spring, PA
Will always use
July 24, 2021
This is great to only have to do every 3 months. I use for both my dogs and never had any issues. Used this with my dog before and had no issues. Very effective
By Angela
Salisbury, MD
Great!
July 1, 2021
Nice to only give 1 chew every 3 months!
By DEBRA M.
KS
Love it!
June 28, 2021
I love the 3 month chew for fleas and ticks. After moving last year from Colorado to Kansas, we hadn't had to deal with fleas. Both of my German Shepherds got fleas and what a disaster for us all. The Bravecto is wonderful!
By Khusbu
NJ
Easy and Works
June 27, 2021
My pup is very fussy so the squeeze tube ones didn't sit well with him. He would rub himself on everything right after. We then switched him to a shot administered every 6 months by his vet but them covid hit and a single vet visit was a nightmare because he couldn't interact with his friends. His vet recommended a couple brand but Bravecto stood out because he needs a pill every 3 months.

It's been working perfect for him ever since and he loves taking it. No issues or troubles.
By JimmyG
Bowie, MD
A product that actually works!
June 22, 2021
My wife and I are foster volunteers with a Min Pin rescue and our home is always full with fosters plus our three. The last thing we need are fleas and ticks. We tried other brands over the last 20 years and Bravecto is hands down the best product to get the job done with zero side effects. Worth every single penny and especially pleased dealing with Entirely pets with their great customer service and super fast shipping! A++
By Don
Eastern Pennsylvania
Bravecto
June 19, 2021
Been using Bravecto for years on my bird dogs. Seems to work as advertised. We hunt in areas where ticks are common. Havenít had any problems so far.
Vet recommended.
Pros
  • Easy to administer. My dogs evidently like the flavor. No chemical collar to deal with.
Cons
  • Quite expensive!!
By Dolores F.
Alabama
The very best!
June 17, 2021
The very best!
By Kevin
Florida
Great Product at Great Price!!!
June 13, 2021
Same product recommended by our Vet but at a much better price.
By radha m.
miami
best flea/tick prevention
June 11, 2021
Bravecto has been the better flea/tick prevention in the past 3years
By Beau?s m.
West TN
Bravecta for us
June 9, 2021
This tablet is so easy to use and dog loves it. Company goes above and beyond when ordering.
Pros
  • Once every 4 months
By Jeremy
CA
great service, prices
June 7, 2021
great, friendly service!
By Debra
Calexico, California
Does the job
June 1, 2021
Love that I can give this med every 3 months and not have to worry about fleas or mites.
By Trecia
California
Perfect
June 1, 2021
This medicine to keep fleas n ticks away is the best Iíve found. And itís only needed to give our fur baby every three months. Itís great.
By Stacey T.
St. Louis mo
Great product!
May 29, 2021
Good for manes as well!
Pros
  • Product works
Cons
  • Dogs don?t like it got to figure ways to give it to the dog
By Christine
Chandler AZ
Great service
May 26, 2021
I was very happy ordering from Entirely Pets. They quickly contacted my vet for verification and shopped it. And their prices are the best!
By Anonymous
north carolina
product is fine but I didn’t order it
May 21, 2021
this showed up without us knowing it would. wasnít on auto order, and we had just ordered some 2 months ago.
By Kim
Florida
Paws-a-tively Fantastic!
May 13, 2021
So glad I found your online pharmacy! Your prices are more affordable than Chewy, and the customer service is outstanding. Thank you!

Merchant Response:Awwww, cute dogs! Take care Kim. :)
By Diane
Thousand Oaks, California
Works for some
May 13, 2021
One of my two small terriers refused to take the Bravecto. I then tried chopping it up and mixing it in his food. He may have ingested some of it but left some of the food. Now I donít know what to do. I donít know if he is partially protected and when I should give him another brand. My other dog ate the Bravecto. I wonít order Bravecto again.
By Denise
Boise, Idaho
Great price and customer service!!
May 13, 2021
I was pleased with the price of the product and the customer service was excellent.
Merchant Response:You are too kind, Thank you Denise.
By Southpaw
Atlanta
Satisfied
May 11, 2021
I've used this product for many years. This website offered a great price and fast shipping.
By Liz
GA
Good
May 3, 2021
I love this pharmacy because it have the Bravecto at a low price, but the down side is that you cannot use coupons or discounts code they sent. Which it make no sense. They should after you paid for shipping.
Pros
  • Good & decent price.
Cons
  • You have to paid for shipping & they will not accept coupons or discount code they sent.
By Erin
New Jersey
Easy to use
May 1, 2021
My dogs love these chews and they last for 3 months. Super easy
By KT
California
Bravecto
April 26, 2021
My dog tolerates these well, I have no issues with the product.

This was my first order from this company, and there was a little snafu in them trying to contact my vet for the prescription. I appreciate Kent calling and letting me know of the delay, however I ended up having to contact my vet and facilitate the prescription verification, whereas I didn't need to when I used other pet med websites. Hopefully it was a one-time issue due to being a new customer, and since the price is better here so I will continue to order from them.
By Tiffany
North Carolina
Apparently delicious!
April 21, 2021
This is the first flea and tick treatment that is easy to give to my dog. She happily takes it and eats it up quickly. So apparently it tastes delicious AND it works well!
Pros
  • Tastes good
  • Last 3 months!!
By AndieP
Portland, Oregon
her tummy tolerates Bravecto
April 17, 2021
Other flea medications upset her stomach
By Phil G.
Roseville, CA
Great Price
April 15, 2021
Received as expected. No complaints.
Cons
  • Didn't give our vet enough time to respond with Rx script

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