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Bravecto for Dogs - 9.9-22 lbs (4 Chews) Video
Bravecto for Dogs - 9.9-22 lbs (4 Chews) Video

Bravecto for Dogs - 9.9-22 lbs (4 Chews)

Item# IWM0526656
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Notices

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Description

Bravecto Chews is the first oral chew for dogs to provide up to 12 weeks of protection against fleas and ticks. One chew provides broad-spectrum and long-lasting protection that starts to kill fleas within 2 hours and controls 4 tick species: black-legged tick (a.k.a. deer tick), American dog tick, brown dog tick, and lone star tick. Bravecto Chews eliminates current flea infestations and prevents new ones from developing for 12 weeks. With one chew, Bravecto Chews is easier to give and less to worry about for you! Bravecto Chews requires a prescription from your veterinarian.

Key Benefits

  • With one dose, Bravecto Chews resets the clock on flea and tick protection by providing effective prevention and treatment for both fleas and ticks for up to 12 weeks.
  • Close to a full year of protection with only 4 doses. No more monthly dosing!
  • No potential for messy application issues and no need to isolate from children or other pets after treatment
  • Fewer doses mean fewer chances to miss a dose decreasing the likelihood of having gaps in protection
  • Dogs love the taste!

How It Works

After giving your dog Bravecto Chews, the medication quickly reaches tissue fluids under your dog's skin. When fleas and ticks feed on your dog, they ingest Bravecto and die. Bravecto Chews kills fleas, prevents flea infestations and kills ticks (black-legged tick (a.k.a. deer tick), American dog tick, and brown dog tick) for 12 weeks. Bravecto Chews also kills lone star ticks for 8 weeks.

Indications

Bravecto kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (blacklegged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)] for 12 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater.

Bravecto is also indicated for the treatment and control of Amblyomma americanum (lone star tick) infestations for 8 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater.

Bravecto Chews is a registered trademark of Intervet Inc., d/b/a Merck Animal Health, a subsidiary of Merck & Co. Inc.

Ingredients

Bravecto Chews 4.4-9.9 lbs:
Active Ingredient (per tablet) Amount
Fluralaner 112.5 mg
Bravecto Chews >9.9-22.0 lbs:
Active Ingredient (per tablet) Amount
Fluralaner 250 mg
Bravecto Chews >22.0-44.0 lbs:
Active Ingredient (per tablet) Amount
Fluralaner 500 mg
Bravecto Chews >44.0-88.0 lbs:
Active Ingredient (per tablet) Amount
Fluralaner 1000 mg
Bravecto Chews >88.0-123.0 lbs:
Active Ingredient (per tablet) Amount
Fluralaner 1,400 mg

Directions

View Bravecto Chews Drug Facts Sheet.

Bravecto should be administered orally as a single dose every 12 weeks according to the Dosage Schedulebelow to provide a minimum dose of 11.4 mg/lb (25 mg/kg) body weight.

Bravecto may be administered every 8 weeks in case of potential exposure to Amblyomma americanum ticks (see Effectiveness).

Bravecto should be administered with food.

Dosage Schedule
Body Weight Ranges (lb) Fluralaner Content (mg) Chews Administered
4.4 - 9.9 112.5 1 (Yellow)
>9.9 - 22.0 250 1 (Orange)
>22.0 - 44.0 500 1 (Green)
>44.0 - 88.0 1000 1 (Blue)
>88.0 - 123.0* 1400 1 (Purple)

*Dogs over 123.0 lb should be administered the appropriate combination of chews

The potential risks ticks pose to pets can be stressful to pet owners wanting to ensure their pet receives effective coverage. Bravecto kills 4 different species of ticks commonly found on dogs and 2 species found on cats to protect your pet for 12 weeks.*5-7

PROTECT YOUR PET AGAINST THESE TICK SPECIES5-7

Contraindications:

There are no known contraindications for the use of the product.

Warnings:

Not for human use. Keep this and all drugs out of the reach of children. Keep the product in the original packaging until use, in order to prevent children from getting direct access to the product.

Do not eat, drink or smoke while handling the product. Wash hands thoroughly with soap and water immediately after use of the product.

Precautions:

Bravecto has not been shown to be effective for 12-weeks duration in puppies less than 6 months of age. Bravecto is not effective against Amblyomma americanum ticks beyond 8 weeks after dosing (see Effectiveness).

Adverse Reactions:

In a well-controlled U.S. field study, which included 294 dogs (224 dogs were administered Bravecto every 12 weeks and 70 dogs were administered an oral active control every 4 weeks and were provided with a tick collar); there were no serious adverse reactions. All potential adverse reactions were recorded in dogs treated with Bravecto over a 182-day period and in dogs treated with the active control over an 84-day period. The most frequently reported adverse reaction in dogs in the Bravecto and active control groups was vomiting.

Percentage of Dogs with Adverse Reactions in the Field Study
Adverse Reaction (AR) Bravecto Group: Percentage of Dogs with the AR During the 182-Day Study (n=224 dogs) Active Control Group: Percentage of Dogs with the AR During the 84-Day Study (n=70 dogs)
Vomiting 7.1 14.3
Decreased Appetite 6.7 0.0
Diarrhea 4.9 2.9
Lethargy 5.4 7.1
Polydipsia 1.8 4.3
Flatulence 1.3 0.0

In a well-controlled laboratory dose confirmation study, one dog developed edema and hyperemia of the upper lips within one hour of receiving Bravecto. The edema improved progressively through the day and had resolved without medical intervention by the next morning.

For technical assistance or to report a suspected adverse drug reaction, contact Merck Animal Health at 1-800-224-5318. Additional information can be found at www.bravecto.com. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth.

Clinical Pharmacology:

Peak fluralaner concentrations are achieved between 2 hours and 3 days following oral administration, and the elimination half-life ranges between 9.3 to 16.2 days. Quantifiable drug concentrations can be measured (lower than necessary for effectiveness) through 112 days. Due to reduced drug bioavailability in the fasted state, fluralaner should be administered with food.

Mode of Action:

Fluralaner is for systemic use and belongs to the class of isoxazoline-substituted benzamide derivatives. Fluralaner is an inhibitor of the arthropod nervous system. The mode of action of fluralaner is the antagonism of the ligand-gated chloride channels (gamma-aminobutyric acid (GABA)-receptor and glutamate-receptor).

Effectiveness:

Bravecto began to kill fleas within two hours after administration in a well-controlled laboratory study. In a European laboratory study, Bravecto killed fleas and Ixodes ricinus ticks and reduced the numbers of live fleas and Ixodes ricinus ticks on dogs by >98% within 12 hours for 12 weeks. In a well-controlled laboratory study, Bravecto demonstrated 100% effectiveness against adult fleas 48 hours post-infestation for 12 weeks. In well-controlled laboratory studies, Bravecto demonstrated ≥93% effectiveness against Dermacentor variabilis, Ixodes scapularis and Rhipicephalus sanguineus ticks 48 hours post-infestation for 12 weeks. Bravecto demonstrated ≥90% effectiveness against Amblyomma americanum 72 hours post-infestation for 8 weeks, but failed to demonstrate ≥90% effectiveness beyond 8 weeks.

In a well-controlled U.S. field study, a single dose of Bravecto reduced fleas by ≥99.7% for 12 weeks. Dogs with signs of flea allergy dermatitis showed improvement in erythema, alopecia, papules, scales, crusts, and excoriation as a direct result of eliminating flea infestations.

Palatability: In a well-controlled U.S. field study, which included 559 doses administered to 224 dogs, 80.7% of dogs voluntarily consumed Bravecto within 5 minutes, an additional 12.5% voluntarily consumed Bravecto within 5 minutes when offered with food, and 6.8% refused the dose or required forced administration.

Animal Safety:

Margin of Safety Study: In a margin of safety study, Bravecto was administered orally to 8 - to 9-week-old puppies at 1, 3, and 5X the maximum label dose of 56 mg/kg at three, 8-week intervals. The dogs in the control group (0X) were untreated.

There were no clinically-relevant, treatment-related effects on physical examinations, body weights, food consumption, clinical pathology (hematology, clinical chemistries, coagulation tests, and urinalysis), gross pathology, histopathology, or organ weights. Diarrhea, mucoid and bloody feces were the most common observations in this study, occurring at a similar incidence in the treated and control groups. Five of the twelve treated dogs that experienced one or more of these signs did so within 6 hours of the first dosing. One dog in the 3X treatment group was observed to be dull, inappetant, with evidence of bloody diarrhea, vomiting, and weight loss beginning five days after the first treatment. One dog in the 1X treatment group vomited food 4 hours following the first treatment.

Reproductive Safety Study: Bravecto was administered orally to intact, reproductively-sound male and female Beagles at a dose of up to 168 mg/kg (equivalent to 3X the maximum label dose) on three to four occasions at 8-week intervals. The dogs in the control group (0X) were untreated.

There were no clinically-relevant, treatment-related effects on the body weights, food consumption, reproductive performance, semen analysis, litter data, gross necropsy (adult dogs) or histopathology findings (adult dogs and puppies). One adult treated dog suffered a seizure during the course of the study (46 days after the second treatment). Abnormal salivation was observed on 17 occasions: in six treated dogs (11 occasions) after dosing and four control dogs (6 occasions).

The following abnormalities were noted in 7 pups from 2 of the 10 dams in only the treated group during gross necropsy examination: limb deformity (4 pups), enlarged heart (2 pups), enlarged spleen (3 pups), and cleft palate (2 pups). During veterinary examination at Week 7, two pups from the control group had inguinal testicles, and two and four pups from the treated group had inguinal and cryptorchid testicles, respectively. No undescended testicles were observed at the time of necropsy (days 50 to 71).

In a well-controlled field study Bravecto was used concurrently with other medications, such as vaccines, anthelmintics, antibiotics, and steroids. No adverse reactions were observed from the concurrent use of Bravecto with other medications.

Storage

Do not store above 86°F (30°C).

FAQ

Yes. Bravecto Chew and Bravecto Topical Solution for Dogs is vet recommended for puppies and dogs 6 months of age or older who weigh at least 4.4 lb.1,2 Bravecto Topical Solution for Cats is vet recommended for kittens and cats 6 months of age or older who weigh at least 2.6 lb.3

Bravecto has a wide margin of safety in dogs who weigh at least 4.4 lb. and cats who weigh at least 2.6 lb. It is also approved for puppies and kittens aged 6 months or older.1-3

Bravecto Chew is approved for use in breeding, pregnant, and lactating dogs.1,4

Bravecto is the only flea and tick treatment that lasts 12 weeks* with 1 convenient chew or topical dose.1-3 Compared to any monthly treatment, your pet is protected nearly 3 times longer with Bravecto.

The long-lasting protection of Bravecto effectively eliminates flea infestations on pets with just 1 dose.7,8 Plus, Bravecto kills ticks faster-killing 100% of attached ticks in 12 hours. Other treatments can take over 48 hours.9

Yes.1-3, 9
After you give your pet Bravecto, it quickly reaches tissue fluids just under your dog's or cat's skin. When fleas and ticks feed, they ingest Bravecto and die.

Bravecto Chew starts killing fleas (Ctenocephalides felis) within 2 hours, and kills ticks (Ixodes ricinus) within 12 hours.*1 Bravecto Chew kills fleas, prevents flea infestations, and kills ticks (black-legged tick, American dog tick, and brown dog tick) for 12 weeks. Bravecto Chew also kills lone star ticks for 8 weeks.1

Bravecto Topical Solution for Dogs reduces fleas by ≥99% and 100% within 24 and 48 hours, respectively, post-infestation for 12 weeks.* It kills ≥93.3% of black-legged ticks, American dog ticks and brown dog ticks after 48 hours for 12 weeks* and kills ≥90% lone star ticks 72 hours post-infestation for 8 weeks.2

Bravecto Topical Solution for Cats kills 100% of fleas within 8 hours. Applied to the base of the skull, your cat will have full-body protection for 12 weeks*-killing fleas, preventing flea infestations, and killing black-legged ticks. Bravecto Topical Solution for Cats also kills American dog ticks for 8 weeks.3

There are no problems reported in field trials in dogs and cats that received Bravecto alongside other commonly used medicines.1-3, 12 However, your veterinarian is your pet's healthcare expert, so it is always best to discuss all of your pet's treatments with them, whether prescription or over-the-counter supplements.
In a US field study where dogs were treated at home, over 93% of dogs ate the chew voluntarily-either by itself or with food.1
Bravecto Chew should be given with food. If a chew is broken or crumbles, make sure your dog still receives the whole dose.
No.
No. Even immediate bathing, shampooing, or swimming won't affect how well Bravecto Chew works because it's not a topical treatment. Coat length and grooming or brushing also have no impact on how well it works.
Yes. Bravecto is approved for use in breeding, pregnant, and lactating dogs.1,4
In a well-controlled laboratory study, Bravecto was shown to be safe in collies known to be MDR-1 gene deficient. Collies with the defect were administered 3 times the deliverable dose and had no adverse events.11
It is always best to discuss your pet's medical treatment with your veterinarian. However, Bravecto has a high margin of safety. In safety studies, Bravecto was tested in healthy dogs and puppies at up to 5 times the recommended dose at 8-week intervals for 3 treatments.1 Therefore, no adverse effects are expected if dogs are inadvertently treated twice with the recommended dose within 12 weeks, but please contact your veterinarian.

If vomiting occurs, check with your vet to decide whether to redose or not; however, if an otherwise healthy dog vomits within 3 hours of receiving Bravecto , it is recommended that the dog be redosed. To help ensure that the dog does not vomit again, it is suggested to wait 24 hours until redosing.

If 4 or more hours have passed before the vomiting occurs, it is likely that the medication has been absorbed and the dog is protected. If the vomiting repeats again, DO NOT give a third chew, and call your veterinarian.

If you suspect that a side effect has taken place as a result of giving the dog Bravecto, please report it to Merck Technical Services at 1-800-224-5318, and follow any advice that they provide.1

Reviews

Review Summary
4.7
282 Reviews
5
75% (211)
4
22% (63)
3
1% (4)
2
1% (2)
1
1% (2)
98% Recommend this product (277 of 282 responses)
By Bob F.
Murrieta, CA
Robert Freiberg
August 25, 2022
excellent product. WE'VE BEEN USING IT FOR YEARS
Pros
  • No mesing with liquid products (frontline)
  • 3 month dose
  • Price only a little higher than frontline
By Mandy B.
Denton Tx
Delivered fast
August 3, 2022
Order was delivered fast
Merchant Response:YES! *Fist pump*
By Jim M.
Yuma, AZ
Excellent
July 21, 2022
3 months between doses and works well dogs like flavor.
By Siao
Los Angeles, CA
Simple, Easy, and Straightforward
July 12, 2022
No issues for our pup, Tofu. Taking it every three months makes it easy to keep track of and gives our pup great protection.
By Hilary
Mooresville, IN
Love This Product
July 5, 2022
Bravecto has been such a good medicine for all four of my pups! Two of my dogs like to go on excursions and come back all dirty but no fleas or ticks. The ticks that are on them after being in the woods for hour are already dead from this medication. 10 out of 10 would recommend!
By Vicky
Russellville, KY
Works great
July 1, 2022
I've used this for my dog for years and thankfully it has worked great. I've never seen a flea or anything else on her! I love that it works for 3 months and I don't have to worry about remembering each month.
Pros
  • Long lasting
Cons
  • The price is a little high
By Hannah
Atlanta
online ordering is easy
May 4, 2022
Once I figured out the website, ordering was easy and the product arrived within a few days without paying extra for shipping. They don't man the phones well.
Unfortunately, prices have gone up :(

Merchant Response:Hannah, we love the pic! We are constantly figuring new ways to make ordering easier and the prices have gone up. We do our best to have the lowest anywhere. Best wishes!
By Melissa
Maine
Authentic and Legit
April 11, 2022
Iím very impressed with this online pharmacy. I have used other big name pet pharmacies previously, and Iím happy with this one! They had my pets prescription approved, shipped, and received all within a few days time. My meds were shipped from Cali and authentic. Iím very happy with Entirely Pets!
By Diane
Michigan
Bravecto 9.9-22 lbs Chews
March 21, 2022
Good price and prompt service. They called veterinarian to get RX. Good communication to me via text on the orderís status.
By Pat
Naples florida
Bravecto
March 14, 2022
Product claims to be chewable however my dog doesnít like it. I have to hide it broken inside of chicken.
Product works well
By Yvonne
CA
Great product
February 26, 2022
My vet recommended this, it works well, and my dogs like it, so it's not a problem giving it to them.
By Manny
East Coast
Could not be easier to keep your pet happy!
January 24, 2022
These are so easy to give our dog. She thinks we're giving her treats. There's no thinking twice, she just eats it right away. I believe it works as it should since she does not seem to scratch very often. We definitely never see any fleas or ticks when it's her bath time.

Nice to set it and forget it. Always gets here on time and it's the best price I've found online. Thank you!
By Playverde
St Petersburg, FL
Best Flea/tick product
December 20, 2021
Living in Florida is a challenge for fleas and after our new pup got fleas even though we were using a topical med, our vet recommended the quarterly chewable. Since then no problems with either dog. I love the convenience and only having to use it 4 times a year.
By Dave
Savannah, GA
Great price
December 12, 2021
Buying medicines for your pet can be taxing and expensive. Entirely Pets makes it a little less expensive and handles all the paperwork from your vet.
By Joyce
Westminster Md
Flea and tick medication
December 12, 2021
I am very happy with my purchase from Entirely Pets . Great service and quick shipping.
Pros
  • In stock
By Denise
Santa Paula, Ca
Great
December 2, 2021
Great product
By FRED
Tennessee
Great for Dogs over 60 Pounds
September 6, 2021
We have ordered these for our two (2) dogs over 60 pounds each. The dogs take these with ease and digests well.
By Andrea
Oklahoma
Bravecto
September 2, 2021
This stuff really works. Even if your dog has invited a flea into your house, once it bites your dog, it dies. Win win.

I love this stuff..
By Bliss
Kerrville, TX
Worked once but not the 2nd time
August 18, 2021
I used this on my small dogs and it worked for 3 months on the first dose, but only a month and half on the 2nd dose. The fleas out here adapt quickly. 😕
By Colleen M.
Napa CA 94559
Flea medication
August 8, 2021
I have used Bravecto for dogs88-123 lbs. in the past. Is effective but does not kill fleas instantly when they are on my dog. May take 2 hours.
By Kristi
Sinking spring, PA
Will always use
July 24, 2021
This is great to only have to do every 3 months. I use for both my dogs and never had any issues. Used this with my dog before and had no issues. Very effective
By Angela
Salisbury, MD
Great!
July 1, 2021
Nice to only give 1 chew every 3 months!
By DEBRA M.
KS
Love it!
June 28, 2021
I love the 3 month chew for fleas and ticks. After moving last year from Colorado to Kansas, we hadn't had to deal with fleas. Both of my German Shepherds got fleas and what a disaster for us all. The Bravecto is wonderful!
By Khusbu
NJ
Easy and Works
June 27, 2021
My pup is very fussy so the squeeze tube ones didn't sit well with him. He would rub himself on everything right after. We then switched him to a shot administered every 6 months by his vet but them covid hit and a single vet visit was a nightmare because he couldn't interact with his friends. His vet recommended a couple brand but Bravecto stood out because he needs a pill every 3 months.

It's been working perfect for him ever since and he loves taking it. No issues or troubles.
By JimmyG
Bowie, MD
A product that actually works!
June 22, 2021
My wife and I are foster volunteers with a Min Pin rescue and our home is always full with fosters plus our three. The last thing we need are fleas and ticks. We tried other brands over the last 20 years and Bravecto is hands down the best product to get the job done with zero side effects. Worth every single penny and especially pleased dealing with Entirely pets with their great customer service and super fast shipping! A++
By Don
Eastern Pennsylvania
Bravecto
June 19, 2021
Been using Bravecto for years on my bird dogs. Seems to work as advertised. We hunt in areas where ticks are common. Havenít had any problems so far.
Vet recommended.
Pros
  • Easy to administer. My dogs evidently like the flavor. No chemical collar to deal with.
Cons
  • Quite expensive!!
By Dolores F.
Alabama
The very best!
June 17, 2021
The very best!
By Kevin
Florida
Great Product at Great Price!!!
June 13, 2021
Same product recommended by our Vet but at a much better price.
By radha m.
miami
best flea/tick prevention
June 11, 2021
Bravecto has been the better flea/tick prevention in the past 3years
By Beau?s m.
West TN
Bravecta for us
June 9, 2021
This tablet is so easy to use and dog loves it. Company goes above and beyond when ordering.
Pros
  • Once every 4 months

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