Biomox Tablets for Dogs, 50-mg, 1 tablet

Biomox (amoxicillin) Tablets and Biomox (amoxicillin) Oral Suspension are a semi-synthetic, broad-spectrum amoxicillin, indicated for the treatment of bacterial dermatitis and soft tissue infections, including abscesses, wounds and lacerations in dogs when caused by susceptible strains of organisms:

• Bacterial Dermatitis due to Staphylococcus aureus, Streptococcus spp., Staphylococcus spp., and E. coli
• Soft Tissue Infections (abscesses, wounds, lacerations) due to Staphylococcus aureus, Streptococcus spp., E. coli, Proteus mirabilis and Staphylococcus spp.

As is true with all antibiotic therapy, appropriate in vitro cultures and sensitivities should be conducted prior to treatment.

• Provides excellent bactericidal activity against a wide variety of common gram-negative and gram-positive pathogens
• Available in 2 convenient formulation options:
• Tablets are available in 50 mg, 100 mg and 200 mg concentrations in bottles of 500 tablets
• Suspension is available in 15 mL and 30 mL sizes with 50 mg/mL potency when reconstituted

Amoxicillin has bactericidal activity against susceptible organisms similar to that of ampicillin. It acts by inhibiting the biosynthesis of bacterial cell wall mucopeptides. Most strains of the following gram-positive and gram-negative bacteria have demonstrated susceptibility to amoxicillin, both in vitro and in vivo: nonpenicillinase-producing staphylococci, alpha- and beta-hemolytic streptococci, Streptococcus faecalis, Escherichia coli and Proteus mirabilis. Amoxicillin does not resist destruction by penicillinase; therefore, it is not effective against penicillinase-producing bacteria, particularly resistant staphylococci. Most strains of Enterobacter and Klebsiella and all strains of Pseudomonas are resistant.

Amoxicillin may be given without regard to meals because it is stable in gastric acid. It is rapidly absorbed following oral administration and diffuses readily into most body fluids and tissues. It diffuses poorly into the brain and spinal fluid except when the meninges are inflamed. Most of amoxicillin is excreted in the urine unchanged.

Inactive Ingredients:

Dibasic Calcium Phosphate, Dihydrate, Magnesium Stearate, Microcrystalline Cellulose and Sodium Starch Glycolate.

View Biomox Detailer Sheet.

Dosage and Administration:

The recommended dosage is 5 mg per pound of body weight administered twice a day for 5 to 7 days. Continue for 48 hours after all symptoms have subsided. If no improvement is noted within 5 days, the diagnosis should be reconsidered and therapy changed.

Directions for Mixing Oral Suspension:

Add sufficient water to the bottle as indicated in the table below and shake vigorously. Each mL of suspension will contain 50 mg of amoxicillin as the trihydrate.

Caution:

Federal Law restricts this drug to use by or on the order of a licensed veterinarian.

Action:

Amoxicillin has bactericidal activity against susceptible organisms similar to that of ampicillin. It acts by inhibiting the biosynthesis of bacterial wall mucopeptides. Most strains of the following gram-positive and gram-negative bacteria have demonstrated susceptibility to amoxicillin, both in vitro and in vivo: nonpenicillinase producing staphylococci, alpha and beta-hemolytic streptococci, Streptococcus faecalis, Eshcherichia coli and Proteus mirabilis. Amoxicillin does not resist destruction by penicillinase; therefore, it is not effective against penicillinase producing bacteria, particularly resistant staphylococci, Most strains of Enterobacter and Klebsiella and all strains of Pseudomonas are resistant.

Amoxicillin may be given without regard to meals because it is stable in gastric acid. It is rapidly absorbed following oral administration and diffuses readily into most body fluids and tissues. It diffuses poorly into the brain and spinal fluid except when the meninges are inflamed. Most of the amoxicillin is excreted in the urine unchanged.

Contraindications:

Use of amoxicillin is contraindicated in animals with a history of an allergic reaction to penicillin.

Adverse Reactions:

Amoxicillin is a semisynthetic penicillin and, therefore, has the potential for producing allergic reactions. Epinephrine and/or steroids should be administered if an allergic reaction occurs.

Warning:

For use in dogs only.

Precautions:

Until adequate reproductive studies are accomplished, Biomox (amoxicillin) tablets should not be used in pregnant or breeding animals.