Activyl Spot-On for Small Dogs & Puppies 14-22 lbs, 6 Month | On Sale | EntirelyPets Rx
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Activyl Spot-On for Small Dogs & Puppies 14-22 lbs, 6 Month

Item# 112173
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Activyl Spot-On for Dogs (14-22 lbs) is the first topical flea treatment to contain indoxacarb, an innocative active ingredient that activates using enzymes inside the flea. Once in contact with the parasites, Activyl's full flea-killing power is activated to eliminate all adult fleas and break the flea life cycle once and for all. The waterproof, fragrance-free formula keeps your kitty protected and itch-free for a full 4 weeks.

Key Benefits

  • Features innovative active ingredients and mode of action.
  • Fast-acting. Starts killing fleas within 8 hours.
  • Breaks the flea life cycle to prevent reinfestation
  • Quick-drying and fragrance-free.
  • Waterproof, remains effective after shampooing and bathing.

Activyl is a registered trademark of Intervet Inc., d/b/a Merck Animal Health, a subsidiary of Merck & Co. Inc.


Active Ingredients

Indoxacarb: (S)-methyl 7-chloro-2, 5-dihydro-2-[[(methoxycarbonyl)
[4-trifluoromethoxy) phenyl]amino]-carbonyl]indeno[1,2-e][1,3,4]
Other Ingredients80.47%


View Activyl for Small Dogs product label.


Place the applicator tip against the skin between the shoulder blades. Squeeze the applicator firmly, applying the entire contents directly onto the skin.

It is a violation of Federal Law to use this product in a manner inconsistent with it's labeling. Refer to the package insert for complete directions for use.


  • Do not allow children to apply product
  • To prevent harm to you and your catm read entire label and directions before each use
  • Follow all directions and precautionary statements carefully.
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  • Do not use on other animals.
  • Do not use more than once a month.
  • Do not have contact or allow children to have contact with treated area untul it is completely dry.
  • Do not allow your dog or cat to ingest this product.

Do not use Activyl Spot on for Dogs on dogs or puppies under 8 weeks of age or weighing less than 4 lbs.

First Aid

If in Eyes

  • Hold eye open and rinse slowly and gently with water for 15-20 minutes.
  • Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye.
  • Call a physician if irritation persists.

If On Skin

  • Take off contaminated clothing.
  • Rinse skin immediately with plenty of water for 15-20 minutes.
  • Call a poison control center or doctor for treatment advice.

If Swallowed

  • Call poison control center or doctor immediately for treatment advice.
  • Have a person sip a glass of water if able to swallow.
  • Do not induce vomiting unless told to do so by the poison control center or doctor.
  • Do not give anything by mouth to an unconscious person.

Possible Side Effects

Monitor your cat after application. Accidental ingestion by the cat may cause intermittent excess salivation. Other immediate post-treatment observations may include licking the face, shaking the head and squinting. these effects should disappear within several minutes following exposure without requiring treatment. If these or other side effects occur consult a veterinarian immediately.


Causes substantial but temporary eye injury. Harmful if absorbed through skin or swallowed. Do not get in eyes or on clothing. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, or using tobacco. Remove and wash contaminated clothing before reuse.

Storage and Disposal

Pesticide storage

Store in a cool, dry place inaccessible to children and pets.

Pesticide Disposal and Container Handling

  • If Empty do not reuse the container. Place in trash or offer for recycling if available.
  • If partly filled call your local solid waster agency for disposal instructions. Never place unused products down any indoor or outdoor drain.


Bathing your pet is not required. According to veterinary industry standards, your pet should not be allowed to swim or be shampooed within 24 hours after applying a topical product.
Activyl can be used in the management of pets with itchy skin due to flea bites—also known as flea allergy dermatitis or FAD.
Fleas can be a year-round problem indoors and outdoors. Applying Activyl every four weeks ensures your dog and cat will be protected from fleas throughout the year.
Activyl remains on the surface of your pet. Fleas get exposed to Activyl when they jump onto a treated animal. It can enter the flea either by moving through their outer surface (called a cuticle) or if the flea happens to ingest some. Since Activyl is on the surface of the pet and not in the pet's bloodstream, fleas do not need to take a blood meal for Activyl to start working.
Fleas tend to hide away unless disturbed. When Activyl starts to work, fleas lose coordination and will sometime move to the coat's surface. This may make them easier to see. Please don't worry; these fleas will die soon.

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