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Zimeta is indicated for the control of pyrexia in horses.
Administer Zimeta by intravenous injection, 1 to 2 times daily, at 12 hour intervals, for up to 2 daysm at a dosage of 20 mg/kg (13.6 mg/lb). The overall number of doses and duration of treatment with Zimeta is dependent on the response observed (fever reduction). Zimeta may be re-administered based on recurrence of fever for up to 3 days. Zimeta is provided in a multi-dose vial and contains a preservative.
Not for use in humans. Keep this and all drugs out of reach of children. In case of accidental exposure, contact a physician immediately. Direct contact with the skin should be avoided. If contact occurs, the skin should be washed immediately with soap and water. As with all injectable drugs causing profound physiological effects, routine precautions should be employed by practitioners when handling and using loaded syringes to prevent accidental self-injection.
Information for Owners or Person Treating Horse: A Client Information Sheet should be provided to the person treating the horse. Treatment administrators and caretakers should be aware of the potential for adverse reactions and the clinical signs associated with NSAID intolerance. Adverse reactions may include colic, diarrhea, and decreased appetite. Serious adverse reactions can occur without warning and, in some situations, result in death. Clients should be advised to discontinue NSAID therapy and contact their veterinarian immediately if any signs of intolerance are observed.
WHAT IS ZIMETA? Zimeta is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID) of the pyrazolone class used to control fever in horses by veterinary prescription only. Fever is an elevation in body temperature due to a variety of infectious and inflammatory conditions in the horse.
HOW TO GIVE ZIMETA TO YOUR HORSE Zimeta should be given according to your veterinarian’s instructions. Do not change the way you give Zimeta to your horse without first speaking with your veterinarian.
WHAT KIND OF RESULTS CAN I EXPECT WHEN MY HORSE IS BEING TREATED WITH ZIMETA FOR A FEVER? Zimeta can control fever that is a result of infection or inflammation; however, it is not a cure for the underlying disease. Consult your veterinarian to identify the underlying cause of your horse’s elevated body temperature. Response to Zimeta varies from horse to horse.
WHICH HORSES SHOULD NOT RECEIVE ZIMETA?
Your horse should not be given Zimeta if he/she:
ZIMETA SHOULD BE GIVEN INTRAVENOUSLY TO HORSES ONLY Zimeta is not for use in horses intended for human food consumption. Do not use in any food producing animals, including lactating dairy animals. People should not take Zimeta. Keep Zimeta and all medications out of the reach of children. Consult a physician in case of accidental ingestion by humans or accidental injection into humans.
WHAT TO TELL/ASK YOUR VETERINARIAN BEFORE GIVING ZIMETA
Talk to your veterinarian about:
Tell your veterinarian if your horse has ever had the following medical problems:
Tell your veterinarian if you plan to breed your horse, or if your mare is pregnant or nursing a foal.
WHAT ARE THE POSSIBLE SIDE EFFECTS THAT MAY OCCUR IN MY HORSE DURING ZIMETA THERAPY? Zimeta, like other NSAIDs, may cause some side effects in individual horses. Serious side effects associated with NSAID therapy can occur with or without warning. Look for the following side effects that may indicate your horse is having a problem with Zimeta or may have another medical problem:
It is important to stop therapy and contact your veterinarian if you think your horse has a medical problem or side effect while taking Zimeta. If you have additional questions about possible side effects, talk with your veterinarian or call KindredBio at 1-888-608-2542.
CAN ZIMETA BE GIVEN WITH OTHER MEDICATIONS? Zimeta should not be given at the same time as with other NSAIDS (for example, aspirin, phenylbutazone, diclofenac, ketoprofen, flunixin, or firocoxib) or systemic corticosteroids (for example, prednisolone, dexamethasone, or triamcinolone).
WHAT DO I DO IN CASE MY HORSE RECEIVES MORE THAN THE PRESCRIBED AMOUNT OF ZIMETA? Consult your veterinarian if your horse receives more than the prescribed amount of Zimeta.
WHAT ELSE SHOULD I KNOW ABOUT ZIMETA? This sheet provides a summary of information about Zimeta (dipyrone injection) and general information about NSAIDs. If you have any questions or concerns about Zimeta or fever talk with your veterinarian.
As with all prescribed medicines, Zimeta should only be given to the horse for which it is prescribed. It should be given to your horse only for the condition for which it is prescribed, at the prescribed dose and duration.
It is important to periodically discuss your horse’s response to Zimeta with your veterinarian. Your veterinarian will determine if your horse is responding as expected and if your horse should continue receiving Zimeta.