Vetivex for Pets - Hartmann's Solution for Injection (5000 mL) - [Body Fluid Replacement] | On Sale | EntirelyPets Rx
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Vetivex for Pets - Hartmann's Solution for Injection (5000 mL) - [Body Fluid Replacement]

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Notices

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Description

Vetivex Veterinary Lactated Ringer's Injection is a prescription, injectable electrolyte solution. It is commonly used to replace body fluid and minerals that are lost through dehydration, gastrointestinal diseases (vomiting and diarrhea), shock, and certain metabolic conditions. Vetivex Veterinary Lactated Ringer's Injection contains sodium lactate, sodium chloride, potassium chloride, and calcium chloride in a sterile fluid without preservatives. If your pet has been diagnosed or is being treated for dehydration, a metabolic disorder, or other medical condition that requires fluid and electrolyte supplementation, your veterinarian may prescribe at-home fluid injection. Consult with your veterinarian about the proper administration and use for your pet.

Key Benefits:

  • Vetivex Veterinary Lactated Ringer's Injection, USP is indicated as a source of water and electrolytes or as an alkanlinizing agent
  • Vetivex LRS is a sterile, nonpyrogenic solution in single dose containers for parenteral administration
  • Two color-coded, identical, dual-purpose ports can be utilized for insertion of the administration set spike or for injection of fluid additives.

Indication:

Vetivex Veterinary Lactated Ringer's Injection, USP is indicated as a source of water and electrolytes or as an alkalinizing agent.

Directions

View Vetivex Drug Facts Sheet.

Dosage & Administration:

As directed by a veterinarian. Dosage is dependent upon the age, weight and clinical condition of the patient, as well as laboratory determinations.Parenteral drug products should be inspected visually for particulate matter anddiscoloration prior to administration whenever solution and container permit.

All solutions for injection contained in plastic containers are intended for administration using sterile equipment and aseptic technique.

Additives may be incompatible. Complete information is not available. Those additives known to be incompatible should not be used. Consult with pharmacist, if available. If, in the informed judgment of the veterinarian, it is deemed advisable to introduce additives, use aseptic technique. Mix thoroughly when additives have been introduced. Do not store solutions containing additives. Discard unused portion.

Overdosage:

In an event of overhydration or solute overload, re-evaluate the patient and institute appropriate corrective measures.

See Warnings, Adverse Reactions and Precautions.

Directions for use of plastic container

To Open

Tear overwrap down side at slit and remove solution bag. Some opacity of the plastic due to moisture absorption during the sterilization process may be observed. This is normal and does not affect the solution quality or safety. The opacity will diminish gradually. Check for minute leaks by squeezing inner bag firmly. If leaks are found, discard solution as sterility may be impaired.

If supplemental medication is desired, follow directions below.

Preparation for Administration

  1. Suspend container from eyelet support.
  2. Remove protector from outlet port at bottom of container.
  3. Attach administration set. Refer to complete directions accompanying set.

To Add Medication

WARNING: Additives may be incompatible.

To add medication before solution administration

  1. Prepare medication site.
  2. Using syringe with 19 to 22 gauge needle, puncture resealable medication port and inject.
  3. Mix solution and medication thoroughly. For high density medication such aspotassium chloride, squeeze ports while ports are uprightand mix thoroughly.

To add medication during solution administration

  1. Close clamp on the administration set to stop the flow to the patient.
  2. Prepare medication site.
  3. Using syringe with 19 to 22 gauge needle, puncture resealable medication port and inject.
  4. Remove container from IV pole and/or turn to an upright position.
  5. Evacuate both ports by squeezing them while container is in the upright position.
  6. Mix solution and medication thoroughly.
  7. Return container to in-use position and continue administration.

Caution:

Federal las (U.S.A.) restricts this drug to use by or on the order of a licensed veterinarian.

Warnings:

Do not administer to horses by intraperitoneal injection.

Veterinary Lactated Ringer's Injection, USP should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency, and in clinical states in which there exists edema with sodium retention.

Veterinary Lactated Ringer's Injection, USP should be used with great care, if at all, in patients with hyperkalemia, severe renal failure, and in conditions in which potassium retention is present.

Veterinary Lactated Ringer's Injection, USP should be used with great care in patients with metabolic or respiratory alkalosis. The administration of lactate ions should be done with great care in those conditions in which there is an increased level or an impaired utilization of these ions, such as severe hepatic insufficiency.

Veterinary Lactated Ringer's Injection, USP should not be administered simultaneously with blood through the same administration set because of the likelihood of coagulation.

The parenteral administration of Veterinary Lactated Ringer's Injection, USP can cause fluid and/or solute overloading resulting in dilution of serum electrolyte concentrations, overhydration, congested states, or pulmonary edema. The risk of dilutional states is inversely proportional to the electrolyte concentrations of the injections. The risk of solute overload causing congested states with peripheral and pulmonary edema is directly proportional to the electrolyte concentrations of the injections.

In patients with diminished renal function, administration of Veterinary Lactated Ringer's Injection, USP may result in sodium or potassium retention.

Veterinary Lactated Ringer's Injection, USP is not for use in the treatment of lacticacidosis.

Adverse Reactions:

Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venousthrombosis or phlebitis extending from the site of injection, extravasation, andhypervolemia. If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures, and save the remainder of the fluid for examination if deemed necessary.

Precautions:

Clinical evaluation and periodic laboratory determinations are necessary to monitor changes in fluid balance, electrolyte concentrations, and acid base balance during prolonged parenteral therapy or whenever the condition of the patient warrants such evaluation.

Veterinary Lactated Ringer's Injection, USP must be used with caution. Excessadministration may result in metabolic alkalosis.

Caution must be exercised in the administration of Veterinary Lactated Ringer ?s Injection, USP to patients receiving corticosteroids or corticotropin. Do not administer unlesssolution is clear and seal is intact.

Storage:

Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat.

It is recommended the product be stored in the moisture barrier overwrap at room temperature (25°C/77°F); brief exposure up to (40°C/104°F) does not adversely affect the product.

FAQ

VETIVEX Hartmann's Solution for Infusion is a sterile, nonpyrogenic, isotonic crystalloid solution for fluid and electrolyte replenishment. VETIVEXHartmann's has an electrolyte profile similar to Lactated Ringer's Solution. Lactated Ringer's Solution (LRS) is a modification of Hartmann's Solution and many references discuss their clinical use and clinical effects as if they are the same, including DiBartola's textbook on fluid therapy. Hartmann'sSolution was developed in the late 1800s to deal with metabolic acidosis in pediatric humans. Alexis Hartmann, a US physician with pediatric interests from St. Louis, developed this balanced electrolyte solution by taking plain Ringer's Solution and adding lactate. Thus, Hartmann's and LRS are often referred to as being the same, since they are both balanced, isotonic electrolyte solutions that contain lactate and have an electrolyte profile similar to plasma.
The addition of lactate helps address conditions of metabolic acidosis by mimicking the body's normal level of bicarbonate ion and providing the body with a readily available source of bicarbonate. Metabolism of lactate by the liver consumes hydrogen ions and generates bicarbonate, and thus has an alkalinizing effect.
Yes, the same contraindications and precautions exist with VETIVEX Hartmann's as for LRS, due to their similar electrolyte profile and osmolarity.

Just like LRS, VETIVEX Hartmann's should not be run through the same infusion set as blood products. The calcium in both LRS and VETIVEX Hartmann's can cause clotting and the possible development of microthrombi.

Based on experience from human medicine, some drugs should not be mixed with Hartmann's Solution. These include drugs containing oxalate, phosphate or carbonate/bicarbonate. Veterinarians should only add drugs to VETIVEX Hartmann's if they are sure they are safe to mix. Incompatibility has been reported with novobiocin sodium, oxytetra-cycline hydrochloride, sodium bicarbonate, sodium calcium edetate, and sulphadiazine sodium when mixed with Hartmann's Solution.

The addition of lactate helps address conditions of metabolic acidosis by mimicking the body's normal level of bicarbonate ion and providing the body with a readily available source of bicarbonate. Metabolism of lactate by the liver consumes hydrogen ions and generates bicarbonate, and thus has an alkalinizing effect.
The 5000mL VETIVEX Hartmann's bags have one port for an IV infusion set and one injection port. They are packaged two per case and have a removable overwrap on them.
Practitioners should use the same infusion rate and volume for each individual patient as they would for LRS, based on the individual patient's hydration, cardiovascular state, and concurrent disease states. Patients should be closely monitored during IV infusion with any fluid and the patient's needs should be reassessed regularly
At this time VETIVEX Hartmann's is only available in 5000mL bags. Dechra expects to introduce other sizes and types ofsterile, intravenous fluids to the US market over time

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