Tobramycin Ophthalmic Solution USP, is a topical prescription antibiotic medication used to treat a wide variety of ophthalmic bacterial infections, including S. aureus and S. epidermidis. It is indicated in the treatment of external infections of the eye and its adnexa caused by susceptible bacteria. Appropriate monitoring of bacterial response to topical antibiotic therapy should accompany the use of Tobramycin Ophthalmic Solution USP.
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Description
Tobramycin Ophthalmic Solution USP, is a sterile, topical antibiotic solution for the treatment of external ophthalmic infections in cats, dogs, and horses. The active ingredient, Tobramycin, is a water-soluble aminoglycoside antibiotic that is effective against a wide array of gram-negative and gram-positive ophthalmic pathogens.
Key Benefits
- Treats eye infections in cats, dogs, and horses
- Effective against a wide array of gram-negative and gram-positive bacteria
How It Works
Tobramycin Ophthalmic Solution USP, is effective against susceptible microorganisms, including: Staphylococci, such as S. aureus and S. epidermidis (coagulase-positive and coagulase-negative), as well as penicillin-resistant strains; Streptococci including some of the Group A-beta-hemolytic species, some nonhemolytic species, and some Streptococcus pneumoniae; Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis, Morganella morganii, most Proteus vulgaris strains, Haemophilus influenzae and H. aegyptius, Moraxella lacunata, Acinetobacter calcoaceticus and some Neisseria species. Bacterial susceptibility studies demonstrate that in some cases, microorganisms resistant to gentamicin retain susceptibility to Tobramycin.
Indications
Tobramycin Ophthalmic Solution, USP is a topical antibiotic indicated in the treatment of external infections of the eyeand its adnexa caused by susceptible bacteria. Appropriate monitoring of bacterial response to topical antibiotic therapyshould accompany the use of Tobramycin Ophthalmic Solution, USP.
Directions
- Use according to your veterinarian's instructions.
- Do not touch the dropper to any surface, including the surface of your pet's eye.
Tip: Adjust the dosage suggested below based on your veterinarian's recommendations.
| Tobramycin Ophthalmic Solution USP, Dosage for Cats | |
|---|---|
| Weight | Dosage |
| All weights | The usual dosage is 1-2 drops to each affected eye every 12 hours, or as prescribed by your veterinarian. |
| Tobramycin Ophthalmic Solution USP, Dosage for Dogs | |
| Weight | Dosage |
| All weights | The usual dosage is 1-2 drops to each affected eye every 12 hours, or as prescribed by your veterinarian. |
| Tobramycin Ophthalmic Solution USP, Dosage for Horses | |
| Weight | Dosage |
| All weights | The usual dosage is 1-2 drops to each affected eye every 12 hours, or as prescribed by your veterinarian. |
Cautions:
Safe use in pregnant pets or pets intended for breeding has not been proven. If your pet's condition worsens or does not improve, stop product administration and consult your veterinarian. Tobramycin Ophthalmic Solution USP, is for topical ophthalmic use only. It is not for injection into the eye. Sensitivity to topically applied aminoglycosides may occur in some pets. If your pet has a reaction to Tobramycin Ophthalmic Solution USP, 0.3%, discontinue use and consult your veterinarian.
Contraindications:
Tobramycin Ophthalmic Solution, USP is contraindicated in patients with known hypersensitivity to any of itscomponents.
Warnings:
For Topical Ophthalmic Use Only - Not For Injection Into The Eye
Sensitivity to topically applied aminoglycosides may occur in some patients. If a sensitivity reaction to TobramycinOphthalmic Solution, USP 0.3% occurs, discontinue use.
Precautions
As with other antibiotic preparations, prolonged use may result in overgrowth of nonsusceptible organisms, including fungi. Ifsuperinfection occurs, appropriate therapy should be initiated. Cross-sensitivity to other aminoglycoside antibiotics mayoccur; if hypersensitivity develops with this product, discontinue use and institute appropriate therapy. Patients should beadvised not to wear contact lenses if they have signs and symptoms of bacterial conjunctivitis.
Storage:
Store at 36°-77°F (2°-25°C).
FAQ
Tell your veterinarian if your pet is known to have hypersensitivity to any ingredients in Tobramycin Ophthalmic Solution USP. Tell your veterinarian if your pet is pregnant, lactating or used for breeding purposes.
The usual dosage is 1-2 drops to each affected eye every 12 hours, or as prescribed by your veterinarian.
Possible side effects of Tobramycin Ophthalmic Solution USP include itching and swelling of the eyelid, as well as redness of the conjunctiva.
Give the missed dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed and give the next regularly scheduled dose. Do not give a double dose unless otherwise directed by your veterinarian.
An overdose of Tobramycin Ophthalmic Solution USP may result in punctate keratitis (an eye disorder caused by the death of small groups of cells on the surface of the cornea), conjunctival erythema (redness), increased lacrimation (excessive tears), edema (swelling), and eyelid itching.
Do not use Tobramycin Ophthalmic Solution USP on pets with known hypersensitivity to any of its components. Tobramycin Ophthalmic Solution USP is for topical ophthalmic use only. Not for injection into the eye. As with other antibiotic preparations, prolonged use may result in an overgrowth of nonsusceptible organisms, including fungi. If superinfection occurs, appropriate therapy should be initiated. Cross-sensitivity to other aminoglycoside antibiotics may occur. If hypersensitivity develops with this product, discontinue use and institute appropriate therapy. Do not touch the dropper to any surface, including the surface of the eye, as this may contaminate the solution.
If Tobramycin Ophthalmic Solution USP is administered concomitantly with systemic aminoglycoside antibiotics, care should be taken to monitor the total serum concentration. Tell your veterinarian if your pet is currently being given any other medications or supplements.
