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Spironolactone is a medication often used as a diuretic or for treatment of heart failure. Spironolactone helps the body to retain the potassium that is sometimes lost in large amounts when using other diuretics. Spironolactone is used to treat congestive heart failure, edema, high blood pressure (hypertension), potassium deficiency, and hyperaldosteronism. Spironolactone works by increasing the levels of water excretion by the kidneys.
Spironolactone inhibits the effect of aldosterone, a hormone that causes the tubules of the kidneys to retain sodium and water. This increases the excretion of water and sodium, while decreasing the excretion of potassium.
Pet | Weight | Dosage |
---|---|---|
Dog | All Weights | The usual dose in dogs and cats is 0.5 mg - 1 mg per pound of body weight every 12 hours |
Cats | All Weights | The usual dose in dogs and cats is 0.5 mg - 1 mg per pound of body weight every 12 hours |
Keep out of the reach of children and pets. Spironolactone should not be used in animals with a known hypersensitivity or allergy to the drug. Do not use in animals that are pregnant or lactating, have high potassium levels in the blood, suffer from hypoadrenocorticism, or suffer from Cushing's disease and are taking the medication mitotane. Use caution when administering to animals with liver or kidney disease Spironolactone may interact with some other medications. Inform your veterinarian of any and all medications your pet may be taking. Spironolactone will cause your pet to urinate more frequently. Store at room temperature.
Spironolactone will cause your pet to urinate more often. Your pet may have more accidents. Your pet needs to eat and drink well while taking this medication or the risk of side effects increases. Contact your veterinarian if your pet is not eating or drinking well, or is vomiting, has diarrhea or becomes lethargic. Do not discontinue the medication unless directed.
This drug is FDA-approved for human use. However, it is common practice for veterinarians to prescribe such drugs for use in dogs and cats.
If any of the following serious side effects occur, stop giving spironolactone and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips; tongue or face; hives); an irregular heartbeat, shortness of breath, fatigue, confusion, weakness, numbness, or decreased urination. Other less serious side effects may occur. Continue giving spironolactone and talk to your veterinarian if your pet experiences headache, dizziness, nausea, diarrhea, decreased appetite, or dry mouth. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.
Store at room temperature away from moisture and heat.
Spironolactone is given orally. Always follow the dosage instructions provided by your veterinarian. If you have difficulty giving the medication, contact your veterinarian.
Food may increase the absorption of Spironolactone. Consult your veterinarian about giving this medication with food.
This medication should only be given to the pet for whom it was prescribed. This medication is given by mouth and can be given with or without food. Never stop giving Spironolactone Tablets suddenly unless your veterinarian instructs you to. Always speak to your veterinarian if you have questions about how to give this medication.