Senvelgo Oral Solution is the first and only FDA-approved SGLT2 (sodium-glucose co-transporter 2) inhibitor specifically developed for cats. This innovative treatment is designed to manage chronic kidney disease (CKD)—a progressive condition commonly affecting aging felines. CKD can cause increased thirst and urination, weight loss, reduced appetite, and a general decline in overall health.
Senvelgo contains velagliflozin, which works by inhibiting the SGLT2 protein in the kidneys. This action reduces the reabsorption of glucose and sodium, helping to lower urinary protein levels (proteinuria)—a key contributor to kidney damage. By targeting this pathway, Senvelgo helps preserve kidney function and improves quality of life in cats with CKD.
Veterinary supervision is recommended during treatment to assess response and adjust dosing if necessary. Monitoring typically includes bloodwork, urinalysis, and evaluation of hydration, glucose levels, and kidney function.
Senvelgo offers a stress-free, once-daily oral solution—ideal for cats who may resist tablets or capsules. It represents a significant advancement in feline nephrology by helping to slow disease progression while enhancing comfort and well-being.
Dosing easier – simple oral once-daily dosing, with minimal risk of clinical hypoglycemic events
Stabilization quicker– provides effective glycemic control within 7 days for most cats, with no dose
adjustments necessary
Monitoring simpler – less monitoring and diagnostics are required for stabilized cats on SENVELGO oral solution
Ingredients
Velagliflozin
Directions
Consult Your Veterinarian: Before using Senvelgo Oral Solution, consult with a veterinarian familiar with feline care. They will provide specific guidance based on your cat's age, weight, and health condition.
Dosage: Administer once daily, exactly as prescribed by your veterinarian.
Administration: Shake well before use. Use the provided oral dosing syringe to ensure accurate measurement. The solution can be administered directly into your cat’s mouth or mixed with a small amount of food.
Monitoring: Regular veterinary check-ups and bloodwork are recommended to monitor kidney function, glucose levels, and overall response to treatment.
Hydration: Ensure your cat has access to clean, fresh water at all times.
Precautions: Do not use in cats with diabetes mellitus, dehydration, or hypotension, unless directed by your veterinarian.
Missed Dose: If a dose is missed, skip it and give the next dose at the regular time. Do not double the dose.
Storage: Store at room temperature. Keep out of reach of children and pets.