Merck Safe-Guard Multi-Species Medicated Dewormer, 5lb

Safe-Guard Multi-Species Medicated Dewormer is a versatile deworming solution approved for use in beef cattle, dairy cattle, horses, swine, turkeys, and a wide variety of zoo and wildlife species. It delivers broad-spectrum internal parasite control across multiple species in a convenient, feed-grade formulation.

Species-Specific Indications & Dosage Instructions

• Cattle (Beef & Dairy): Controls lungworms, barberpole worms, brown stomach worms, small stomach worms, hookworms, intestinal worms, bankrupt worms, and nodular worms.
  Feeding Directions: 1 lb per 1,100 lbs body weight as a single-day treatment.
  Retreatment: May be needed every 4–6 weeks.
  Withdrawal: 13-day slaughter withdrawal; no milk withdrawal required.


• Equine (Horses): Controls large strongyles, small strongyles, pinworms, and ascarids.
  Feeding Directions:
  • Strongyles & Pinworms: 1 lb per 1,100 lbs body weight in a one-day treatment.
  • Ascarids: 2 lbs per 1,100 lbs body weight in a one-day treatment.
  Retreatment: Typically every 6–8 weeks.


• Swine: Controls lungworms, large roundworms, nodular worms, small stomach worms, whipworms, and kidney worms (adults and larvae).
  Feeding Directions: 1.92 oz per 200 lbs body weight daily for 3 consecutive days.
  Withdrawal: No slaughter withdrawal required.


• Growing Turkeys: Controls roundworms, cecal worms (adults and larvae), and blackhead (Histomoniasis).
  Feeding Directions: 14.5 grams per ton of feed, fed as sole ration for 6 days.
  Withdrawal: No slaughter withdrawal required.


• Zoo & Wildlife Animals:
  • Bighorn Sheep: For lungworms — 10 mg/kg body weight daily for 3 days.
  • Feral Swine: For kidney worms, roundworms, nodular worms — 3 mg/kg body weight daily for 3 days.
  • Ruminants (Antelopes, Goats, and related species): For small stomach worms, thread-necked intestinal worms, barberpole worms, and whipworms — 2.5 mg/kg body weight daily for 3 days.

Safe-Guard Multi-Species Medicated Dewormer is a registered trademark of Intervet Inc., d/b/a Merck Animal Health, a subsidiary of Merck & Co., Inc.

Active Ingredient (per pound):

Fenbendazole – 0.5% (2.27 g/lb)

Inactive Ingredients:

Dehydrated Alfalfa Meal, Roughage Products, Calcium Carbonate, Mineral Oil.

Safe-Guard 0.5% Alfalfa-Based Dewormer Pellets for Dairy and Beef Cattle – Dosage Guidelines

Administer Safe-Guard pellets at a dose of 5 mg of fenbendazole per kg (2.27 mg/lb) of body weight in a single-day treatment. Ensure accurate dosing based on estimated body weight.

Feeding Instructions: Provide Safe-Guard medicated pellets as a single-day treatment. No prior withdrawal of feed or water is necessary. Following the feeding rates above ensures proper intake of 2.27 mg fenbendazole per pound of body weight.

In environments with continued parasite exposure, retreatment may be required after 4 to 6 weeks. Consult your veterinarian for ongoing parasite management strategies.

Residue Warning:

Cattle must not be slaughtered for human consumption within 13 days of the last treatment. No milk withdrawal period is required for dairy cattle.

Important Safety Information:

Keep this and all medications out of reach of children. Not for human use.