PrednisTab for Dogs - (Prednisolone) 20mg (500 Tabs) - [Autoimmune Disease Treatment] | On Sale | EntirelyPets Rx
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PrednisTab for Dogs - (Prednisolone) 20mg (500 Tabs) - [Autoimmune Disease Treatment]

Item# IWM020302
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PrednisTab reduces inflammation and is also used to suppress the actions of the immune system. It is used in the treatment of autoimmune diseases such as lupus or pemphigus, autoimmune hemolytic anemias, asthma and inhalant allergies (atopy), cancers, brain swelling, certain types of colitis, certain kidney diseases, and Addison's disease.

Key Benefits

  • PrednisTab is a powerful anti-inflammatory medication that treats inflammation from allergies and more
  • Also helps treat auto-immune diseases, and certain types of brain swelling and cancers
  • It is used to treat Addison's disease, in which the body does not produce enough corticosteroids
  • Oral dosage regimen can be effectively individualized for your pet by your veterinarian

How It Works

PrednisTab has an effect on virtually every organ system in the body. PrednisTab is a corticosteroid that blocks the production of substances that trigger allergic and inflammatory actions. PrednisTab is used to modify the body's immune response. At lower doses it helps to reduce inflammation by decreasing the activity of certain cells and chemicals produced by the body that cause inflammation. At higher doses, it can suppress the immune system by decreasing the number of cells necessary for a proper immune response.


PrednisTab tablets and solutions are indicated in the following conditions:

  • Endocrine Disorders
  • Rheumatic Disorders
  • Collagen Diseases
  • Dermatologic Diseases
  • Allergic States
  • Ophthalmic Diseases
  • Respiratory Diseases
  • Hematologic Disorders
  • Neoplastic Diseases
  • Edematous States
  • Gastrointestinal Diseases
  • Miscellaneous


Dogs and Cats: PrednisTab is used for a wide variety of conditions in both dogs and cats. It may be used in emergency situations including, anaphylactic reactions, spinal chord trauma, and many forms of shock. It is used in the management and treatment of immune-mediated disease such as immune-mediated hemolytic anemia, or thrombocytopenia: many CNS disorders: some neoplasia: dermatologic diseases: allergic reactions such as asthma, hives, and itching: inflammatory orthopedic diseases: endocrine disorders including Addison's: respiratory disease with an inflammatory component, inflammatory bowel diseases and many other conditions. Cats may require higher doses than dogs to achieve a clinical response, but they are less likely to develop adverse side effects.

Horses: PrednisTab is given systemically to decrease inflammatory and immune responses. For years it was used orally to treat Chronic Obstructive Pulmonary Disease (COPD), and other allergic or immune-mediated disorders. Recent studies show that horses do not absorb oral PrednisTab, but they do absorb oral prednisolone. Other corticosteroids are preferred for intra-articular use.

2.5 mg per 10 lb (4.5 kg) body weight per day. Average total daily oral doses for dogs are as follows:
Weight Dosage
5 to 20 lb (2 to 9 kg) body weight 1.25 to 5 mg
20 to 40 lb (9 to 18 kg) body weight 5 to 10 mg
40 to 80 lb (18 to 36 kg) body weight 10 to 20 mg
80 to 160 lb (36 to 73 kg) body weight 20 to 40 mg
The total daily dose should be given in divided doses, 6 to 10 hours apart.

Side Effects:

Systemic side effects to corticosteroids are generally dependent on dose and duration of treatment. Short-term use of PrednisTab is unlikely to cause adverse effects. Adverse effects are more common in animals on immunosuppressive doses. Side effects seen in dogs include polyuria, polydipsia, polyphagia, poor hair coat, GI disturbance, diarrhea, vomiting, weight gain, GI ulceration, pancreatitis, lipidemia, elevated liver enzymes, diabetes mellitus, muscle wasting, and possible behavioral changes. Polyuria, polydipsia, polyphagia may be seen in dogs even on short-term therapy. Although cats are less likely to develop side effects than dogs, occasionally polyuria, polydipsia, polyphagia, weight gain, GI disturbances, and behavioral changes occur. Corticosteroids can cause or worsen gastric ulcers.


Chronic or inappropriate use of corticosteroids can cause life-threatening hormonal and metabolic changes. Adverse effects due to corticosteroid treatment usually occur with long-term administration of the drug, especially when high doses are used. Alternate day therapy with short-acting preparations is preferred. Animals who have received long-term therapy should be withdrawn slowly by tapering the dosage and prolonging the interval between doses. Corticosteroids suppress the immune response. Animals receiving systemic corticosteroids may be more susceptible to bacterial or viral infections. Systemic corticosteroids can mask signs of infection, such as an elevated temperature. Systemic corticosteroids are contraindicated in patients with systemic fungal infections. (The treatment of Addison's disease may be considered an exception.) Animals in hepatic failure should receive prednisolone rather than PrednisTab. Corticosteroids should be avoided or used very carefully in young animals both because of immune suppression and the risk of GI ulcers. Corticosteroids have been implicated as a cause of laminitis in horses and ponies. Corticosteroids should be avoided during pregnancy and lactation unless the benefits outweigh the risks. Large doses in early pregnancy may be teratogenic. Corticosteroids can induce labor in cattle and have been used to terminate a pregnancy in dogs.


Without first talking to your veterinarian, don't give your pet any over-the-counter or other prescription medications while giving PrednisTab. There are possible side effects, including insomnia, nausea, vomiting, upset stomach, and fatigue. Tell your veterinarian if your pet has kidney or liver disease, heart disease, stomach ulcers, hypothyroidism, diabetes mellitus, or any other medical conditions. Keep this medication away from children and pets.


Store PrednisTab at room temperature away from moisture and heat. Keep this medication away from children and pets.


PrednisTab is a corticosteroid used to treat various inflammatory and allergy conditions as well as other diseases. PrednisTab is sold per tablet and requires a prescription from your veterinarian.
PrednisTab is a prescription medication that is used in dogs and cats. PrednisTab is available as 1 mg, 5 mg, 10 mg, 20 mg, and 50 mg scored tablets. The usual dose for dogs and cats is determined based on the condition being treated and the pet's response to treatment. PrednisTab should not be stopped suddenly. There should be a gradual reduction in dosage before stopping. PrednisTab should be taken with food to lessen stomach upset.
Do not give PrednisTab to your pet if the pet has a serious bacterial, viral or fungal infection. PrednisTab weakens the pet's immune response and its ability to fight infections. Tell your veterinarian if your pet has kidney or liver disease, heart disease, stomach ulcers, hypothyroidism, diabetes mellitus or any other medical conditions. Also tell your veterinarian if your pet is pregnant or lactating.
Give this medication exactly as directed by your veterinarian. Do not give more or less than is prescribed by the veterinarian. If you do not understand the directions, ask your pharmacist or veterinarian to explain them to you. Keep plenty of water available for your pet. PrednisTab should be given with food.
If any of the following serious side effects occur, stop giving PrednisTab and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips, tongue or face; hives), increased blood pressure or sudden weight gain. Other less serious side effects may occur. Continue giving PrednisTab and talk to your veterinarian if your pet experiences insomnia, nausea, vomiting or stomach upset, fatigue, muscle weakness or joint pain, problems with diabetes control or increased hunger or thirst. Other side effects that occur rarely, usually with high doses of PrednisTab include thinning of the skin, cataracts, glaucoma, behavior changes. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.
If you give one dose daily, give the missed dose as soon as remembered. However, if you don't remember until the next day, skip the missed dose and give only the regular daily dose. If you give more than one dose daily, either give the missed dose as soon as remembered, or give two doses the next dose time. If you give one dose every other day, give the missed dose as soon as remembered, then go back to the regular every other day schedule.
Seek emergency veterinary medical treatment if an overdose is suspected.
Avoid sources of infection. Do not use any vaccines without checking with the veterinarian.
Do not give any other over-the-counter or prescription medications, including herbal products, during treatment with PrednisTab without first talking to your veterinarian. Many other medications can interact with PrednisTab resulting in side effects or altered effectiveness.

Ask your veterinarian what dose will provide the most benefit while minimizing any side effects. Also discuss how long the treatment period will be and what type of outcome is expected. You and your veterinarian should talk about any other treatment options that are recommended for your pet.

Tell your veterinarian if your pet has diabetes; stomach ulcers; Cushings disease; a bacterial, viral or fungal infection; heart, liver or kidney disease; may be pregnant or is nursing, or if you intend to breed your dog.

Notify your veterinarian of any other medications or supplements your dog is taking. Also if your dog has had any reactions to previous medications.


Review Summary
7 Reviews
86% (6)
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14% (1)
86% Recommend this product (6 of 7 responses)
By shirley b.
Great product and service
December 16, 2023
I received my order in a timely fashion. The personnel that took my order were very nice and extremely informative. I would recommend .Entirely Pets to anyone .
New Orleans, LA
Excellent customer service
October 11, 2023
I ordered a couple of prescription items and opted to send in the original scripts. Customer service contacted me by email and phone to remind me to send them. As soon as they were received, my items were promptly shipped.
By Ann
Franklin, Ohio
RX for elderly cat
August 3, 2023
This was handled very fast with help in getting the medication delivered very fast. Greatly appreciated. Phone reps very courteous.
By Rebecca
Chattanooga, TN
Excellent pricing and fast shipping
March 30, 2021
Happy to have found this site. It saves me a lot on the steroid that is helping my cat with her allergies. Shipping is generally pretty fast, too.
By Josiane
Fast Service
March 5, 2020
Would use again !
By Jeffrey T.
There are less expensive sites available!
February 16, 2020
Won't be using this company again. There are less expensive sites available for the same medication.

EntirelyPets took almost 2 weeks to get this scipt sent out for my Dog.

Good thing I had enough remaining medication to cover the time frame of waiting on this company!
  • TOO SLOW in sending out the scripts.
By Vicki
Great price
September 20, 2019
My dachshund will be on these for life (he is 16 now) and my mini dachshund May need them a couple yrs down the road!! My vet cost were $30 for 25 pills, I pd this twice and finally found entirely pets, thank god. Cost

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