Phenylbutazone is a prescription medication FDA approved for use in horses. Phenylbutazone tablets should be given with food. Phenylbutazone injectable solution should be administered intravenously. The injectable solution does not include a syringe. Phenylbutazone Oral Paste should be administered by the mouth. Phenylbutazone should not be given to animals who are dehydrated or have stomach ulcers, anemia or bleeding disorders, or liver, kidney or heart disease.
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Phenylbutazone (BUTE) 1gm (per tab)
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- Description
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Description
Phenylbutazone helps to relieve swelling by blocking specific enzymes. It may be prescribed by your veterinarian to treat a variety of temporary inflammatory conditions, such as a pulled tendon, acute laminitis or joint problems. This form of Bute comes in a convenient oral tablet.
Key Benefits
- Relieves pain and inflammation
- Particularly good for osteoarthritis
- Reduces fever
- Inexpensive
How it works
Phenylbutazone is a non-steroidal anti-inflammatory drug (NSAID) which through its anti-inflammatory action can relieve pain, reduce inflammation and reduce fever.
Indications
For the relief of inflammatory conditions associated with the musculoskeletal system in horses.
Directions
- Phenylbutazone for horses is a prescription medication.
- Phenylbutazone is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with fractures, arthritis, and painful injuries to the limbs and joints.
The oral dose for horses is 2 gm to 4 gm (2 to 4 tablets per 1,000 lbs. of body weight) every 24 hours or as directed by your veterinarian.
Cautions:
Do not give Phenylbutazone to pregnant or lactating mares. Do not give Phenylbutazone with other NSAIDs, corticosteroids, or other ulcer-causing medications. Phenylbutazone should not be given to horses that are dehydrated or have stomach ulcers, anemia, bleeding disorders, or liver, kidney or heart disease.
Precautions:
Stop medication at the first sign of gastrointestinal upset, jaundice or blood dyscrasia. Authenticated cases of agranulocytosis associated with the drug have occurred in man; fatal reactions, although rare, have been reported in dogs after long-term therapy. To guard against this possibility, conduct routine blood counts at weekly intervals during the early phase of therapy and at intervals of two weeks thereafter. Any significant fall in the total white blood cell count, relative decrease in granulocytes, or black or tarry stools should be regarded as a signal for immediate cessation of therapy and institution of appropriate counter-measures.In the treatment of inflammatory conditions associated with infections, specific anti-infective therapy is required.
Warning:
Not for use in horses intended for food.
Storage:
Store Phenylbutazone Tablets at room temperature, away from moisture and heat. Phenylbutazone injectable solution must be kept in the refrigerator at all times. To ensure proper temperature, Phenylbutazone injectable solution requires overnight shipping at an additional cost.
FAQ
Phenylbutazone is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with fractures, arthritis and painful injuries to the limbs and joints. Phenylbutazone may be used for purposes other than those listed in this medication guide.
Tell your veterinarian if your horse has ever had an allergic reaction to phenylbutazone or any other NSAID. Tell your veterinarian if your horse has any liver, kidney or heart disease. Tell your veterinarian if your horse is pregnant or lactating. Talk to your veterinarian about the appropriate syringe to use with Phenylbutazone Injectable Solution.
Give this medication exactly as directed by your veterinarian. If you do not understand the directions, ask your pharmacist or veterinarian to explain them to you. Tablets should be given with food. Phenylbutazone injectable solution should be administered intravenously. Store this medication at room temperature. Keep out of the reach of children and pets.
Give the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and give the next one as directed. Do not give a double dose of the medication.
In the event of overdose, contact your veterinarian or veterinary emergency room. Symptoms of overdose may include decreased urine production and blood in the urine, jaundice (yellowing of the skin, gums and eyes), pale gums, weakness, and ulcers.
Do not use phenylbutazone in animals allergic to it or other NSAIDs. Do not use in pregnant or lactating mares. Do not give phenylbutazone with other NSAIDs, corticosteroids, or other ulcer causing medications.
Side effects that may occur when using phenylbutazone may include ulcers, kidney damage, bloody stool, decreased white blood cells and platelets as well as an allergic reaction (facial swelling, hives, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, coma). Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your horse.
Use caution when giving phenylbutazone with phenytoin, warfarin, sulfonamides, glipizide, digoxin, barbiturates, rifampin, chlorpheniramine or diphenhydramine. Talk to your veterinarian or pharmacist before using phenylbutazone with any prescription or over the counter medications, including vitamins, minerals and herbal supplements.
Your pharmacist has additional information about phenylbutazone written for health professionals that you may read.
