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Nobivac Canine 1-DAPPv+L4 (25 Doses)
- Notice
- Description
- Ingredients
- Directions
- Reviews
Notices
This item will ship via Express 1-2 day mail with a flat rate fee of $36.95 and will be packed in an insulated box with ice packs. Items that are required to ship this method will be listed in the item description. Orders placed after 2:00 PM ET (11:00 AM PT) may not end up being able to ship out the same day.
Restrictions: All foreign orders are ineligible. Free shipping is ineligible.
Note: Vaccine orders are only shipped out on Mon-Wed. due to Express service only being able to deliver during weekdays. We cannot be responsible for vaccine or other refrigerated orders that are delayed because no one is present at the time it is delivered.
Description
Nobivac Canine 1-DAPPv+L4 is a comprehensive 5-way combination vaccine recommended for the vaccination of healthy dogs. It provides protection against canine distemper virus (CDV), adenovirus type 1 (hepatitis), canine parainfluenza virus (CPiV), canine parvovirus (CPV), and four key Leptospira serovars (L. canicola, L. icterohaemorrhagiae, L. pomona, and L. grippotyphosa). View official product page.
Key Benefits
- Offers broad-spectrum protection against distemper, hepatitis, parainfluenza, and all known strains of canine parvovirus, including CPV-2c1,2
- Formulated with CPV-2b — one of the most prevalent field strains — to ensure effective immunization
- High antigenic mass (titer), low passage for a fast and robust immune response
- Proven to override maternal antibodies, ensuring early protection for puppies3
- Only leptospirosis vaccine that protects against both mortality and urinary shedding from all four targeted Leptospira serovars
- Demonstrated prevention of mortality caused by L. canicola, L. icterohaemorrhagiae, L. pomona, and L. grippotyphosa3
- Protects against infectious canine hepatitis caused by adenovirus type 1
- Single-dose formula that offers essential core and non-core disease coverage in one convenient injection
Indications
- For the vaccination of healthy dogs as an aid in the prevention of disease caused by:
- Canine Distemper Virus (CDV)
- Canine Adenovirus Type 1 (CAV-1) – Infectious Canine Hepatitis
- Canine Parainfluenza Virus (CPiV)
- Canine Parvovirus (CPV) including CPV-2c
- For the prevention of leptospirosis, mortality, and urinary shedding caused by:
- Leptospira canicola
- Leptospira icterohaemorrhagiae
- Leptospira pomona
- Leptospira grippotyphosa
- Safe and effective for use in healthy dogs 8 weeks of age or older
Nobivac is a registered trademark of Intervet Inc., d/b/a Merck Animal Health, a subsidiary of Merck & Co., Inc.
Ingredients
Active Ingredients in Nobivac Canine 1‑DAPPv+L₄ (1 mL Dose)
| Component | Type / Details |
|---|---|
| Canine Distemper Virus | Modified live virus antigen |
| Canine Adenovirus Type 2 (protects CAV-1) | Modified live virus antigen |
| Canine Parainfluenza Virus | Modified live virus antigen |
| Canine Parvovirus (CPV‑2b) | Modified live virus antigen, includes protection against CPV‑2c |
| Leptospira canicola, L. icterohaemorrhagiae, L. pomona, L. grippotyphosa | Inactivated bacterins (killed)** |
| Gentamicin & Amphotericin B | Preservatives (<1%) |
Directions
Dosage and Administration
Shake the vial of Nobivac Lepto4 thoroughly and aseptically transfer its contents to the Nobivac Canine 1-DAPPv vial. Mix gently until fully dissolved. Use the entire contents immediately after reconstitution.
Administer one dose (1 mL) subcutaneously. The initial dose can be given to puppies 8 weeks of age or older. Repeat every 2 to 4 weeks until the dog reaches 12 weeks of age. A minimum of two doses is required for primary immunization. Annual revaccination with a single dose is recommended.
- Subcutaneous or intramuscular injection
- Two 1 mL doses given 2–4 weeks apart
- Repeat dosing every 2–4 weeks until 12 weeks of age
- Annual revaccination with one dose is recommended
Following the American Veterinary Medical Association (AVMA) Vaccination Principles, revaccination schedules should be tailored based on the veterinarian-client-patient relationship.
Safety Information
- Clinically proven safe across a wide range of dog breeds and ages
- Now enhanced with VacciPure™ filtration technology for increased purity and consistency
- Please refer to the product label for complete safety details
Precautions
- Store between 2°C and 7°C (35°F to 45°F)
- Do not freeze
- Do not mix with other vaccines unless specified
- Use only new, non-chemically sterilized needles and syringes
- Dispose of vaccine containers and any unused product by burning
Warnings
- Contains gentamicin and amphotericin B as preservatives
- Vaccinate only healthy, non-parasitized dogs
- Do not vaccinate pregnant dogs
- Adverse reactions such as anaphylaxis or other immune-mediated responses may occur
- Antidote: Epinephrine, corticosteroids, and antihistamines may be used depending on reaction severity
- Maternal antibodies may interfere with vaccine efficacy; timing may vary based on maternal titer and antibody absorption
