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Misoprostol is used for the treatment and prevention of stomach ulcers in dogs. It is used to treat stomach ulcers, especially those due to the use of non-steroidal anti-inflammatory drugs such as aspirin and some prescription arthritis medications.
Misoprostol is a prescription medication for the treatment and prevention of stomach ulcers. It is used to treat stomach ulcers, especially those due to the use of non-steroidal anti-inflammatory drugs such as aspirin and some prescription arthritis medications (see patient info sheet for examples). Misoprostol is also used to decrease the toxic effects to the kidney resulting from the use of cyclosporine.
Misoprostol treats and prevents gastric (stomach) ulcers by protecting the stomach lining and decreasing stomach acid formation. Misoprostol is a synthetic form of a prostaglandin.
Misoprostol is indicated for reducing the risk of NSAID (nonsteroidal anti-inflammatory drugs,including aspirin)–induced gastric ulcers in patients at high risk of complications from gastric ulcer,e.g., the elderly and patients with concomitant debilitating disease, as well as patients at high risk ofdeveloping gastric ulceration, such as patients with a history of ulcer. Misoprostol has not been shownto reduce the risk of duodenal ulcers in patients taking NSAIDs. Misoprostol should be taken for theduration of NSAID therapy. Misoprostol has been shown to reduce the risk of gastric ulcers incontrolled studies of 3 months' duration. It had no effect, compared to placebo, on gastrointestinal painor discomfort associated with NSAID use.
Ingredients | Type | Typical Amount |
---|---|---|
Misoprostol | Active | 100 µg or 200 µg per tablet |
Hydrogenated castor oil | Inactive | Tablet excipient |
Hypromellose | Inactive | Coating/stabilizer |
Microcrystalline cellulose | Inactive | Binder/filler |
Sodium starch glycolate | Inactive | Disintegrant |
This standard formulation is designed to provide the correct therapeutic dose of Misoprostol with reliable tablet performance, ensuring effective ulcer protection in dogs under veterinary supervision.
Administer Misoprostol exactly as prescribed by your veterinarian. Do not adjust the dosage or discontinue use without veterinary approval. Wear disposable gloves when handling this medication. To minimize side effects, it is recommended to give Misoprostol with food.
Common side effects may include:
These effects are often mild and temporary, resolving within a few days. If symptoms worsen or persist, contact your veterinarian. In rare cases, uterine contractions or vaginal bleeding may occur—Misoprostol must not be used in pregnant animals due to the risk of abortion.
This medication is FDA-approved for human use, but is commonly prescribed by veterinarians for dogs, cats, and horses under extra-label usage.
Store Misoprostol in a tightly sealed container at controlled room temperature: 68°F to 77°F (20°C to 25°C). Keep out of reach of children and pets.