Mirtazapine is used in behavior modification in dogs and cats on occasion but has been used more often as an appetite stimulant in pets that are reluctant to eat. It is commonly used for long term control of diseases like Inflammatory Bowel Disease in Dogs (IBD) and in elderly renal failure cats. Some veterinarians may also use it for the treatment of separation anxiety in dogs, inappropriate urination (urine spraying) and anxiety in cats. The use of this drug in cats with interstitial cystitis is based on the condition's association with stress, and increased central nervous system activity occurring as a result of this disorder (because of frequent and painful urination).
Mirtazapine causes a side effect that stimulates appetite. It also has strong anti-nausea properties that block signals from the intestine and stomach that communicate with the vomit center of the brain.
Mirtazapine tablets are indicated for the treatment of major depressive disorder.
Tip: It is important to find out the cause of the loss of appetite in your pet and treat the underlying condition and not just the symptoms.
Keep out of reach of children. Safety of Mirtazapine is unproven in pregnant and lactating pets.
Mirtazapine should be used with caution in pets with known cardiac disease or cerebrovascular disease that could be exacerbated by hypotension. Pets with renal impairment, renal failure, or hepatic disease may require lower doses of mirtazapine and should be monitored while on mirtazapine therapy.
This drug is FDA-approved for human use. However, it is common practice for veterinarians to prescribe such drugs for use in dogs and cats.
Mirtazapine may cause a drop in blood pressure or an elevation in heart rate. Drowsiness and serotonin syndrome are potential side effects. Occasionally, mirtazapine has been reported to cause abnormalities in blood cell lines developing in the bone marrow. If a pet is known to have leukemia, low platelets, or some other blood disease mirtazapine can still be used but extra monitoring tests are probably in order.