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Nuflor (Florfenicol) Injectable Solution for Cattle is an antibiotic indicated for the treatment of bovine respiratory disease
Nuflor (Florfenicol) Injectable Solution for Cattle is an antibiotic indicated for the treatment of bovine respiratory disease (BRD) and foot rot, and for the control of respiratory disease in cattle at high risk for developing BRD.
INDICATIONS: NUFLOR Injectable Solution is indicated for treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni, and for the treatment of bovine interdigital phlegmon (foot rot, acute interdigital necrobacillosis, infectious pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus. Also, it is indicated for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.
DOSAGE AND ADMINISTRATION: For treatment of bovine respiratory disease (BRD) and bovine interdigital phlegmon (foot rot): NUFLOR Injectable Solution should be administered by intramuscular injection to cattle at a dose rate of 20 mg/kg body weight (3 mL/100 lbs). A second dose should be administered 48 hours later. Alternatively, NUFLOR Injectable Solution can be administered by a single subcutaneous (SC) injection to cattle at a dose rate of 40 mg/kg body weight (6 mL/100 lbs). Do not administer more than 10 mL at each site. The injection should be given only in the neck.
NOTE: Intramuscular injection may result in local tissue reaction which persists beyond 28 days. This may result in trim loss of edible tissue at slaughter. Tissue reaction at injection sites other than the neck is likely to be more severe.
For control of res piratory dis eas e in cattle at high-ris k of developing BRD: Nuflor Injectable Solution should be administered by a single subcutaneous injection to cattle at a dose rate of 40 mg/kg body weight (6 mL/100 lbs). Do not administer more than 10 mL at each site. The injection should be given only in the neck.
NUFLOR Injectable Solution DOSAGE GUIDE | ||
---|---|---|
ANIMAL WEIGHT(lbs) | IM NUFLOR DOSAGE 3.0 mL/100 lb Body Weight(mL) | SC NUFLOR DOSAGE 6.0 mL/100 lb Body Weight(mL) |
100 | 3.0 | 6.0 |
200 | 6.0 | 12.0 |
300 | 9.0 | 18.0 |
400 | 12.0 | 24.0 |
500 | 15.0 | 30.0 |
600 | 18.0 | 36.0 |
700 | 21.0 | 42.0 |
800 | 24.0 | 48.0 |
900 | 27.0 | 54.0 |
1000 | 30.0 | 60.0 |
Clinical improvement should be evident in most treated subjects within 24 hours of initiation of treatment. If a positive response is not noted within 72 hours of initiation of treatment, the diagnosis should be re-evaluated.
CONTRAINDICATIONS: Do not use in animals that have shown hypersensitivity to florfenicol.
WARNINGS: NOT FOR HUMAN USE. KEEP OUT OF REACH OF CHILDREN. This product contains materials that can be irritating to skin and eyes. Avoid direct contact with skin, eyes, and clothing. In case of accidental eye exposure, flush with water for 15 minutes. In case of accidental skin exposure, wash with soap and water. Remove contaminated clothing. Consult a physician if irritation persists. Accidental injection of this product may cause local irritation. Consult a physician immediately. The Material Safety Data Sheet (MSDS) contains more detailed occupational safety information.
For customer service, adverse effects reporting, and/or a copy of the MSDS, call 1-800-211-3573.
PRECAUTIONS: Not for use in animals intended for breeding purposes. The effects of florfenicol on bovine reproductive performance, pregnancy, and lactation have not been determined. Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy. Intramuscular injection may result in local tissue reaction which persists beyond 28 days. This may result in trim loss of edible tissue at slaughter. Tissue reaction at injection sites other than the neck is likely to be more severe.
RESIDUE WARNINGS: Animals intended for human consumption must not be slaughtered within 28 days of the last intramuscular treatment. Animals intended for human consumption must not be slaughtered within 38 days of subcutaneous treatment. This product is not approved for use in female dairy cattle 20 months of age or older, including dry dairy cows. Use in these cattle may cause drug residues in milk and/or in calves born to these cows. A withdrawal period has not been established in pre-ruminating calves. Do not use in calves to be processed for veal.
ADVERSE REACTIONS: Inappetence, decreased water consumption, or diarrhea may occur transiently following treatment.