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Fludrocortisone (FLORINEF) is available by prescription only. Fludrocortisone is an extra-label drug used when the adrenal gland has lost the ability to produce cortisol and aldosterone. Fludrocortisone is used to treat hypoadrenocorticism, or Addison’s disease. Hypoadrenocorticism is an autoimmune disease that destroys the outer layers of the adrenal gland. These layers are responsible for producing vital hormones, including cortisol and aldosterone. Fludrocortisone replaces aldosterone to help the kidneys balance the concentration of sodium and potassium in your pet’s body.
Fludrocortisone acetate is a mineralocorticoid, similar in action to aldosterone, which acts on the kidney to help balance the concentration of sodium and potassium in your pet's body.
Fludrocortisone acetate tablets USP, 0.1 mg are indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.
Pet | Weight | Dosage |
---|---|---|
Dogs | All weights | The usual dose is 0.009mg per pound of pet's body weight once daily with food |
Cats | All weights | The usual dose is 0.1mg once daily with food |
If your pet experiences increased blood pressure, sudden weight gain, difficulty breathing, hives, or swelling of the lips, tongue or face, stop giving Fludrocortisone and seek emergency veterinary medical attention.
Do not give Fludrocortisone to animals who have a serious bacterial, viral or fungal infection because this drug weakens the immune response and its ability to fight infections. Tell your veterinarian if your pet has kidney or liver disease, heart disease, stomach ulcers, hypothyroidism, diabetes mellitus or any other medical conditions. Also, tell your vet if the pet is pregnant or lactating.
This drug is FDA-approved for human use. However, it is common practice for veterinarians to prescribe such drugs for use in dogs and cats.
Possible side effects include insomnia; nausea, vomiting or stomach upset; fatigue; muscle weakness or joint pain; problems with diabetes control; or increased hunger or thirst. If you notice these symptoms, contact your veterinarian, but do not discontinue use unless instructed. Rare side effects include thinning of the skin, cataracts, glaucoma, behavior changes; these typically occur when taking higher doses of the drug. Talk to your vet about any side effect that seems unusual or bothersome to your pet.
Store at controlled room temperatures of 59° - 86°F. Avoid excessive heat.