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Diphenhydramine is an antihistamine. Diphenhydramine is used to treat allergic reactions, atopic dermatitis, or itchy skin, motion sickness, vomiting, coughing, or anxiety. Histamines are chemicals that are released in the body in response to inflammation or allergies. When histamines attach to H-1 receptors in the body, it causes the blood vessels to widen which leads to swelling and itchiness. Diphenhydramine blocks the effects of histamines, reducing inflammation and itchiness.
Diphenhydramine comes in 25 mg minitabs or 50 mg capsules, and is a generic version of Benadryl. As an antihistamine, it counteracts the effect of histamine, which causes symptoms like itching and sneezing.
Diphenhydramine HcL is an ethanolamine derivative H1 receptor antihistamine, with secondary sedative, anticholinergic, antitussive, and antiemetic effects. In other words, this drug blocks the part of the brain that responds to allergens (histamine), relaxes them, keeps them from coughing, and prevents nausea. Most offten used in pets that suffer from seasonal allergies, this medication is helpful when dealing with rashes, like pruritus or insect bites, or when dealing with motion sickness. Available in multiple strengths (prescription and OTC) and as a tablet or an injectable, there are a number of different ways to optimize the way your pet receives their treatment depending on their condition.
Active Ingredients (per Minitab): | |
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Product | Active Ingredients |
Diphenhydramine HCl 25 mg Minitab | Diphenhydramine 25 mg |
Other Ingredients (per capsule): Corn starch, D&C red #27, Dicalcium Phosphate, Magnesium Stearate, Microcrystalline Cellulose, Polyethylene Glycol, Polyvinyl Alcohol, Silicon Dioxide, Stearic Acid, Talc, Titanium Dioxide. | |
Active Ingredients (per capsule): | |
Product | Active Ingredients |
Diphenhydramine HCl 50 mg Minitab | Diphenhydramine 50 mg |
Other Ingredients (per capsule): Colloidal Silicon Dioxide, Croscamellose Sodium, D&C Red #28, FD&C Blue #1, FD&C Red #3, FD&C Red #40, Gelatin, Lactose, Magnesium Stearate. May also contain Polysorbate 80 and iron oxide. |
Tip: The slow release capsule should NOT be mixed or dissolved in food. Do not use sinus or cold medications containing diphenhydramine in your pet.
Diphenhydramine (Generic Benadryl) Dosage for Cats | |
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Weight | Dosage |
All weights | Give 0.5-2 mg/lb of pet's body weight every 8-12 hours |
Diphenhydramine (Generic Benadryl) Dosage for Dogs | |
Weight | Dosage |
All weights | Give 0.5-2 mg/lb of pet's body weight every 8-12 hours |
This medication should not be used in pregnant or nursing animals. Do not use the diphenhydramine available in combination with sinus or cold medicines in your pet.
Side effects of diphenhydramine include drowsiness, dry mouth and urinary retention. Rarely, vomiting and diarrhea can occur.
Store this medication at room temperature, away from excess heat, light and moisture. Keep this medication in the container it came in, tightly closed. Store this medication at room temperature, away from excess heat, light, and moisture. Do not store in the bathroom. Throw away any medication that is outdated or no longer needed. Keep medication away from children and pets.