Clemastine 2.68 mg (100 Tabs) | On Sale | EntirelyPets Rx
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Clemastine 2.68 mg (100 Tabs) (Manufacturer may vary)

Item# IWM033106
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Clemastine is an antihistamine for dogs and cats that is very effective in treating allergy symptoms, including itchy skin (pruritus) and skin inflammation of Atopic Dermatitis. Similar to and often more effective than other antihistamines, Clemastine acts by blocking the H1 receptor on tissues and suppresses inflammatory reactions caused by histamine.

Key Benefits

  • Clemestine antihistamine helps relieve itching caused by allergies
  • Clemestine treats itching caused by atopy
  • Clemestine has less of a sedative effect than other antihistamines

How It Works

Clemastine is a selective histamine H1 antagonist. It binds to the histamine H1 receptor, and blocks histamine, allowing for temporary relief of allergy symptoms.


Clemastine Fumarate Tablets, USP, 2.68 mg are indicated for the relief of symptoms associated withallergic rhinitis such as sneezing, rhinorrhea, pruritus, and lacrimation. Clemastine Fumarate Tablets,USP, 2.68 mg are also indicated for the relief of mild, uncomplicated allergic skin manifestations ofurticaria and angioedema.

It should be noted that clemastine fumarate is indicated for the dermatologic indications at the 2.68 mgdosage level only.


It is important to follow your Veterinarian's prescription for your pet

Dogs/Puppies of all weights: 1/2 - 1 tablet every 12 hours

Cats/Kittens of all weights: 1/2 tablet every 12 hours

Possible Side Effects

Side effects of Clemastine vary with cats and dogs.

In dogs it's most commonly sedation, hyperactivity, and dry mouth.

In cats, diarrhea is most common.

The side effects of clemastine in dogs are sedation, paradoxical hyperactivity, and dryness of the mouth.


Clemastine fumarate should be used with caution in those with a history of bronchial asthma, increased pressure caused by fluid inside eye, hyperthyroidism, heart disease and high blood pressure.

This drug is FDA-approved for human use. However, it is common practice for veterinarians to prescribe such drugs for use in dogs and cats.


Use with caution when given with sedatives or tranquilizers.

Use with caution in animals with prostate or bladder conditions, sever cardiac failure or glaucoma.

Use with caution when given to pregnant or nursing animals.

Do not use in animals that are allergic to it.


Clemastine is a prescription antihistamine for dogs and cats. Clemastine is used in for the treatment of allergies and atopy, primarily to stop itching.
  • Prescription antihistamine in tablet form for cats and dogs.
  • Clemastine is used to stop itching due to allergies and atopy.
  • Less sedative side effect compared to other antihistamines.
Clemastine is given by mouth. Duration of treatment depends on the reason for and response to treatment. Always follow the dosage instructions provided by your veterinarian. If you have difficulty giving the medication, contact your veterinarian. This medication should only be given to the pet for whom it was prescribed.
Clemastine works by blocking the actions of histamine in the body. Histamine is the chemical responsible for many of the symptoms seen when an allergic reaction occurs. Clemastine belongs to a group of antihistamines called H1 blockers.
Clemastine will not cure allergies, but can help reduce the symptoms. The effects will disappear if the medication is discontinued. Results may not be immediate and it can take several weeks to see improvement.

Talk to your veterinarian about what tests and exams may be necessary while your pet is taking Clemastine. Also, discuss how long the treatment period will be and what type of outcome is expected. You and your veterinarian should talk about any other treatment options that are recommended for your pet.

Tell your veterinarian if your pet has prostate disease, urinary obstruction, heart disease, glaucoma, or gastrointestinal obstruction, is pregnant or may be used for breeding.

Notify your veterinarian of any other medications or supplements your pet is taking. Also if your pet has had any reactions to previous medications.

If you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give two doses at once.
Clemastine is not a cure, and symptoms will return if the Clemastine is discontinued. This medication may cause sedation.
Not for use in animals hypersensitive (allergic) to it. Use with caution in animals with glaucoma, enlarged prostate, severe cardiac failure, or obstruction of the urinary bladder (problems urinating), or obstruction of the pylorus (junction between the stomach and intestine). Do not use in working animals (military dogs, police dogs, seeing eye dogs, hearing dogs, etc.) as it may cause too much sedation. Clemastine may enter the milk and have adverse effects on the young.

Dogs: Side effects include dry mouth, sleepiness, sedation, or hyperexcitability.

Cats: Most common side effect is diarrhea.

If you know or suspect your pet has had an overdose, contact your veterinarian immediately.
Consult your veterinarian before using Clemastine with vitamins and supplements, other central nervous system (CNS) depressant drugs such as barbiturates or antidepressants, monoamine oxidase inhibitors (MAOIs), such as furazolidone, selegiline (Anipryl), isoniazid, or amitraz (an ingredient in some tick collars, and in Mitaban, a treatment for mange), or flea and tick collars, since interactions may occur.

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