Cimetidine Oral Solution 300mg/5ml (240ml) (Manufacturer may vary)

Cimetidine has been used for the treatment and/or prophylaxis of gastric, abomasal and duodenal ulcers, uremic gastritis, stress-related or drug-induced erosive gastritis, esophagitis, duodenal gastric reflux and esophageal reflux. It has also been employed to treat hypersecretory conditions associated with gastrinomas and systemic mastocytosis. Cimetidine is also used as a immunomodulating agent in dogs.

Key Benefits

• Treats and prevents gastric, abomasal and duodenal ulcers
• Used for the treatment of uremic, stress related, or drug induced erosive gastritis
• Effective in alleviating esophagitis
• Aids in the management of acid reflux, protecting the esophagus
• Used to reduce inflammation of the stomach lining when caused by kidney failure
• Sometimes used as an antihistamine in the treatment of mast cell tumors

How It Works

Cimetidine works by limiting acid production in the stomach through the blockage of histamine action. It helps prevent ulcers from forming while also treating ulcers that have already formed.

It can also treat:

• Esophageal reflux
• Gastric reflux
• Esophagitis (inflammation of the esophagus)
• Gastritis (inflammation of the stomach)

Cimetidine is available in 100 mg, 150 mg, 200 mg and 300 mg tablets liquid form of 300mg per 5ml and injectable form. The normal dose is 3 to 5 mg per pound, administered orally every six to eight hours. The dosage could be changed depending on the specific condition to be treated. Make sure to complete the course to prevent relapse.

Follow your Veterinarian's prescription and instructions for your pet.

Precautions:

Though it is relatively safe to use under the supervision of a veterinarian, cimetidine could cause side effects in some animals. Make sure that the pet is not hypersensitive to this drug before administering Cimetidine animals with liver or kidney disease should be treated with utmost caution. Cimetidine can interact with other medications such as antacids, metoclopramide, sucralfate, digoxin and diazepam. Be careful while administering this drug in older pets or those with blood diseases.

Though Cimetidine is not approved for use in animals, it could be legally prescribed by veterinarians as an extra-label drug. Cimetidine is used in dogs and cats to treat mast cell tumors, gastritis inflammation of the stomach, esophagitis inflammation of the esophagus, and gastric or esophageal reflux.Chronic cimetidine therapy is found to be beneficial for uremic dogs under hemodialysis, to suppress the circulating concentrations of immuno reactive parathyroid hormone.

Side Effect:

Serious side effects are generally not prevalent however contact the veterinarian if the animal develops labored breathing or rapid heartbeat during the course of treatment with cimetidine. Cimetidine overdosage might result in tachycardia and respiratory failure, and should these symptoms persist, respiratory support and beta-adrenergic blockers should be used.

Overdosage

Clinical experience with cimetidine overdosage is limited. In laboratory animals, very high dosages have been associated with tachycardia and respiratory failure. Respiratory support and beta-adrenergic blockers have been suggested for use should these symptoms occur.

Storage:

Store at temperatures from 68° - 77°F.