Bravecto for Dogs - 22-44 lbs (4 Chews) | On Sale | EntirelyPets Rx
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Bravecto for Dogs - 22-44 lbs (4 Chews) Video
Bravecto for Dogs - 22-44 lbs (4 Chews) Video

Bravecto for Dogs - 22-44 lbs (4 Chews)

Item# IWM0526666
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BRAVECTO ON SALE! Discounted price can be seen in cart.

*Can't be combined with other offers.


Bravecto is the first oral chew for dogs to provide up to 12 weeks of protection against fleas and ticks. One chew provides broad-spectrum and long-lasting protection that starts to kill fleas within 2 hours and controls 4 tick species: black-legged tick (a.k.a. deer tick), American dog tick, brown dog tick, and lone star tick. Bravecto Chews eliminates current flea infestations and prevents new ones from developing for 12 weeks. With one chew, Bravecto Chews is easier to give and less to worry about for you! Bravecto Chews requires a prescription from your veterinarian.

Key Benefits:

  • With one dose, Bravecto Chews resets the clock on flea and tick protection by providing effective prevention and treatment for both fleas and ticks for up to 12 weeks.
  • Close to a full year of protection with only 4 doses. No more monthly dosing!
  • No potential for messy application issues and no need to isolate from children or other pets after treatment
  • Fewer doses mean fewer chances to miss a dose decreasing the likelihood of having gaps in protection
  • Dogs love the taste!

How It Works

After giving your dog Bravecto Chews, the medication quickly reaches tissue fluids under your dog's skin. When fleas and ticks feed on your dog, they ingest Bravecto and die. Bravecto Chews kills fleas, prevents flea infestations and kills ticks (black-legged tick (a.k.a. deer tick), American dog tick, and brown dog tick) for 12 weeks. Bravecto Chews also kills lone star ticks for 8 weeks.


Bravecto kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (blacklegged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)] for 12 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater.

Bravecto is also indicated for the treatment and control of Amblyomma americanum (lone star tick) infestations for 8 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater.


  • Generic Name: Fluralaner
  • Usage: Prevention, Treatment
  • Repels or Prevents: Fleas
  • Kills or Treats: Fleas, Ticks
  • Lifestage: Adult, Senior, Puppy
  • Breed Size: Small Breeds, Medium Breeds
  • Product Form: Chew
  • Strength: 500 mg Fluralaner


Bravecto Chews 4.4-9.9 lbs:
Active Ingredient (per tablet) Amount
Fluralaner 112.5 mg
Bravecto Chews >9.9-22.0 lbs:
Active Ingredient (per tablet) Amount
Fluralaner 250 mg
Bravecto Chews >22.0-44.0 lbs:
Active Ingredient (per tablet) Amount
Fluralaner 500 mg
Bravecto Chews >44.0-88.0 lbs:
Active Ingredient (per tablet) Amount
Fluralaner 1000 mg
Bravecto Chews >88.0-123.0 lbs:
Active Ingredient (per tablet) Amount
Fluralaner 1,400 mg


View Bravecto Chews Drug Facts Sheet.

Bravecto should be administered orally as a single dose every 12 weeks according to the Dosage Schedulebelow to provide a minimum dose of 11.4 mg/lb (25 mg/kg) body weight.

Bravecto may be administered every 8 weeks in case of potential exposure to Amblyomma americanum ticks (see Effectiveness).

Bravecto should be administered with food.

Dosage Schedule
Body Weight Ranges (lb) Fluralaner Content (mg) Chews Administered
4.4 - 9.9 112.5 1 (Yellow)
>9.9 - 22.0 250 1 (Orange)
>22.0 - 44.0 500 1 (Green)
>44.0 - 88.0 1000 1 (Blue)
>88.0 - 123.0* 1400 1 (Purple)

*Dogs over 123.0 lb should be administered the appropriate combination of chews

The potential risks ticks pose to pets can be stressful to pet owners wanting to ensure their pet receives effective coverage. Bravecto kills 4 different species of ticks commonly found on dogs and 2 species found on cats to protect your pet for 12 weeks.*5-7



There are no known contraindications for the use of the product.


Not for human use. Keep this and all drugs out of the reach of children. Keep the product in the original packaging until use, in order to prevent children from getting direct access to the product.

Do not eat, drink or smoke while handling the product. Wash hands thoroughly with soap and water immediately after use of the product.


Bravecto has not been shown to be effective for 12-weeks duration in puppies less than 6 months of age. Bravecto is not effective against Amblyomma americanum ticks beyond 8 weeks after dosing (see Effectiveness).

Adverse Reactions:

In a well-controlled U.S. field study, which included 294 dogs (224 dogs were administered Bravecto every 12 weeks and 70 dogs were administered an oral active control every 4 weeks and were provided with a tick collar); there were no serious adverse reactions. All potential adverse reactions were recorded in dogs treated with Bravecto over a 182-day period and in dogs treated with the active control over an 84-day period. The most frequently reported adverse reaction in dogs in the Bravecto and active control groups was vomiting.

Percentage of Dogs with Adverse Reactions in the Field Study
Adverse Reaction (AR) Bravecto Group: Percentage of Dogs with the AR During the 182-Day Study (n=224 dogs) Active Control Group: Percentage of Dogs with the AR During the 84-Day Study (n=70 dogs)
Vomiting 7.1 14.3
Decreased Appetite 6.7 0.0
Diarrhea 4.9 2.9
Lethargy 5.4 7.1
Polydipsia 1.8 4.3
Flatulence 1.3 0.0

In a well-controlled laboratory dose confirmation study, one dog developed edema and hyperemia of the upper lips within one hour of receiving Bravecto. The edema improved progressively through the day and had resolved without medical intervention by the next morning.

For technical assistance or to report a suspected adverse drug reaction, contact Merck Animal Health at 1-800-224-5318. Additional information can be found at For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at

Clinical Pharmacology:

Peak fluralaner concentrations are achieved between 2 hours and 3 days following oral administration, and the elimination half-life ranges between 9.3 to 16.2 days. Quantifiable drug concentrations can be measured (lower than necessary for effectiveness) through 112 days. Due to reduced drug bio-availability in the fasted state, fluralaner should be administered with food.

Mode of Action:

Fluralaner is for systemic use and belongs to the class of isoxazoline-substituted benzamide derivatives. Fluralaner is an inhibitor of the arthropod nervous system. The mode of action of fluralaner is the antagonism of the ligand-gated chloride channels (gamma-aminobutyric acid (GABA)-receptor and glutamate-receptor).


Bravecto began to kill fleas within two hours after administration in a well-controlled laboratory study. In a European laboratory study, Bravecto killed fleas and Ixodes ricinus ticks and reduced the numbers of live fleas and Ixodes ricinus ticks on dogs by >98% within 12 hours for 12 weeks. In a well-controlled laboratory study, Bravecto demonstrated 100% effectiveness against adult fleas 48 hours post-infestation for 12 weeks. In well-controlled laboratory studies, Bravecto demonstrated ?93% effectiveness against Dermacentor variabilis, Ixodes scapularis and Rhipicephalus sanguineus ticks 48 hours post-infestation for 12 weeks. Bravecto demonstrated ?90% effectiveness against Amblyomma americanum 72 hours post-infestation for 8 weeks, but failed to demonstrate ?90% effectiveness beyond 8 weeks.

In a well-controlled U.S. field study, a single dose of Bravecto reduced fleas by ?99.7% for 12 weeks. Dogs with signs of flea allergy dermatitis showed improvement in erythema, alopecia, papules, scales, crusts, and excoriation as a direct result of eliminating flea infestations.

Palatability: In a well-controlled U.S. field study, which included 559 doses administered to 224 dogs, 80.7% of dogs voluntarily consumed Bravecto within 5 minutes, an additional 12.5% voluntarily consumed Bravecto within 5 minutes when offered with food, and 6.8% refused the dose or required forced administration.

Animal Safety:

Margin of Safety Study: In a margin of safety study, Bravecto was administered orally to 8 - to 9-week-old puppies at 1, 3, and 5X the maximum label dose of 56 mg/kg at three, 8-week intervals. The dogs in the control group (0X) were untreated.

There were no clinically-relevant, treatment-related effects on physical examinations, body weights, food consumption, clinical pathology (hematology, clinical chemistries, coagulation tests, and urinalysis), gross pathology, histopathology, or organ weights. Diarrhea, mucoid and bloody feces were the most common observations in this study, occurring at a similar incidence in the treated and control groups. Five of the twelve treated dogs that experienced one or more of these signs did so within 6 hours of the first dosing. One dog in the 3X treatment group was observed to be dull, inappetant, with evidence of bloody diarrhea, vomiting, and weight loss beginning five days after the first treatment. One dog in the 1X treatment group vomited food 4 hours following the first treatment.

Reproductive Safety Study: Bravecto was administered orally to intact, reproductively-sound male and female Beagles at a dose of up to 168 mg/kg (equivalent to 3X the maximum label dose) on three to four occasions at 8-week intervals. The dogs in the control group (0X) were untreated.

There were no clinically-relevant, treatment-related effects on the body weights, food consumption, reproductive performance, semen analysis, litter data, gross necropsy (adult dogs) or histopathology findings (adult dogs and puppies). One adult treated dog suffered a seizure during the course of the study (46 days after the second treatment). Abnormal salivation was observed on 17 occasions: in six treated dogs (11 occasions) after dosing and four control dogs (6 occasions).

The following abnormalities were noted in 7 pups from 2 of the 10 dams in only the treated group during gross necropsy examination: limb deformity (4 pups), enlarged heart (2 pups), enlarged spleen (3 pups), and cleft palate (2 pups). During veterinary examination at Week 7, two pups from the control group had inguinal testicles, and two and four pups from the treated group had inguinal and cryptorchid testicles, respectively. No undescended testicles were observed at the time of necropsy (days 50 to 71).

In a well-controlled field study Bravecto was used concurrently with other medications, such as vaccines, anthelmintics, antibiotics, and steroids. No adverse reactions were observed from the concurrent use of Bravecto with other medications.


Do not store above 86°F (30°C).


Yes. Bravecto Chew and Bravecto Topical Solution for Dogs is vet recommended for puppies and dogs 6 months of age or older who weigh at least 4.4 lb.1,2 Bravecto Topical Solution for Cats is vet recommended for kittens and cats 6 months of age or older who weigh at least 2.6 lb.3

Bravecto has a wide margin of safety in dogs who weigh at least 4.4 lb. and cats who weigh at least 2.6 lb. It is also approved for puppies and kittens aged 6 months or older.1-3

Bravecto Chew is approved for use in breeding, pregnant, and lactating dogs.1,4

Bravecto is the only flea and tick treatment that lasts 12 weeks* with 1 convenient chew or topical dose.1-3 Compared to any monthly treatment, your pet is protected nearly 3 times longer with Bravecto.

The long-lasting protection of Bravecto effectively eliminates flea infestations on pets with just 1 dose.7,8 Plus, Bravecto kills ticks faster-killing 100% of attached ticks in 12 hours. Other treatments can take over 48 hours.9

Yes.1-3, 9
After you give your pet Bravecto, it quickly reaches tissue fluids just under your dog's or cat's skin. When fleas and ticks feed, they ingest Bravecto and die.

Bravecto Chew starts killing fleas (Ctenocephalides felis) within 2 hours, and kills ticks (Ixodes ricinus) within 12 hours.*1 Bravecto Chew kills fleas, prevents flea infestations, and kills ticks (black-legged tick, American dog tick, and brown dog tick) for 12 weeks. Bravecto Chew also kills lone star ticks for 8 weeks.1

Bravecto Topical Solution for Dogs reduces fleas by ≥99% and 100% within 24 and 48 hours, respectively, post-infestation for 12 weeks.* It kills ≥93.3% of black-legged ticks, American dog ticks and brown dog ticks after 48 hours for 12 weeks* and kills ≥90% lone star ticks 72 hours post-infestation for 8 weeks.2

Bravecto Topical Solution for Cats kills 100% of fleas within 8 hours. Applied to the base of the skull, your cat will have full-body protection for 12 weeks*-killing fleas, preventing flea infestations, and killing black-legged ticks. Bravecto Topical Solution for Cats also kills American dog ticks for 8 weeks.3

There are no problems reported in field trials in dogs and cats that received Bravecto alongside other commonly used medicines.1-3, 12 However, your veterinarian is your pet's healthcare expert, so it is always best to discuss all of your pet's treatments with them, whether prescription or over-the-counter supplements.
In a US field study where dogs were treated at home, over 93% of dogs ate the chew voluntarily-either by itself or with food.1
Bravecto Chew should be given with food. If a chew is broken or crumbles, make sure your dog still receives the whole dose.
No. Even immediate bathing, shampooing, or swimming won't affect how well Bravecto Chew works because it's not a topical treatment. Coat length and grooming or brushing also have no impact on how well it works.
Yes. Bravecto is approved for use in breeding, pregnant, and lactating dogs.1,4
In a well-controlled laboratory study, Bravecto was shown to be safe in collies known to be MDR-1 gene deficient. Collies with the defect were administered 3 times the deliverable dose and had no adverse events.11
It is always best to discuss your pet's medical treatment with your veterinarian. However, Bravecto has a high margin of safety. In safety studies, Bravecto was tested in healthy dogs and puppies at up to 5 times the recommended dose at 8-week intervals for 3 treatments.1 Therefore, no adverse effects are expected if dogs are inadvertently treated twice with the recommended dose within 12 weeks, but please contact your veterinarian.

If vomiting occurs, check with your vet to decide whether to redose or not; however, if an otherwise healthy dog vomits within 3 hours of receiving Bravecto , it is recommended that the dog be redosed. To help ensure that the dog does not vomit again, it is suggested to wait 24 hours until redosing.

If 4 or more hours have passed before the vomiting occurs, it is likely that the medication has been absorbed and the dog is protected. If the vomiting repeats again, DO NOT give a third chew, and call your veterinarian.

If you suspect that a side effect has taken place as a result of giving the dog Bravecto, please report it to Merck Technical Services at 1-800-224-5318, and follow any advice that they provide.1


Review Summary
314 Reviews
76% (240)
21% (66)
1% (4)
1% (2)
1% (2)
98% Recommend this product (309 of 314 responses)
By Diana
Western North Carolina
August 11, 2023
Bravecto was the choice of our veterinarian. They warned about online orders not always being of
proper quality. Still, I took a gamble with the 15% discount. I received what I ordered (an annual
4-pack, 3 month doses) The bill was as originally priced with the discount applied. The expiration
dates cover the year of RX needed. The earlier online complaints about "billing different than pricing" seems to be solved. No problem. And the order came within a week. No complaints on delivery.
We had used Bravecto for six months from our vet. We have seen/felt no ticks on our long haired English Shepherd. It seems to be the top choice online. None so far, assuming the RX is good for its date. Brevecto has worked so far.
By Jill
July 18, 2023
Great pricing. Fast shipping.
By Diana
Deville, LA
July 10, 2023
Came in a timely manner. Order was complete.
By Jessie
June 29, 2023
I placed the order and they did all the work‚€¶ and wayyyyyy cheaper than the vet!!!! I will continue to order my pets meds from here from now on‚€¶ highly recommend
Easy shipped right to my door Price is amazing
By Sharon
Tallahassee Florida
Bravecto Flea Prevention for Dogs
May 31, 2023
Been using Bravecto works better than any other flea prevention on the market.
By Deborah
North Carolina
Quality Product at Excellent Price
May 17, 2023
We've typically ordered products for our dog from one supplier; however, because of rising prices, I decided to compare prices across the internet before placing the last order. EntirelyPets Pharmacy, without a doubt, has the absolute best prices. Website is easy to navigate and shipping was quick.
By Jane
Cape Coral Fl
May 11, 2023
product arrived on time and was item ordered.
By Richard
Best Price, not so fast
May 5, 2023
I give 5 stars for price. But the process is super slow. They dont accept e-mailed prescriptions. So the process to get in touch with my Vet even though I had the hand written script was very slow. I could have mailed the script which would have taken longer.
Other than that it was ok
Price and shipping Approval process slow.
By joanne
excellent product
May 2, 2023
excellent product
By Linz B.
Great Value
May 2, 2023
Communication by seller was the best of any we have purchased from and the price could not be beaten!
Merchant Response:Hello Linz, Thank you so much! Our team tries its best to make sure we are communicating with you every step of the way so that we can provide the best turnaround time for shipping. Sincerely, EntirelyPets Pharmacy
By Laura
Great product
April 23, 2023
Great product but so expensive
Merchant Response:Hello Laura, We're glad to hear you enjoy the product, Entirely Pets try to offer the best price we can for all of our products, please make sure you check your email for promotional codes and the homepage for further promotions and sales going on. Sincerely, EntirelyPets Pharmacy
Great product Expensive
By Karen
Ballwin, MO
April 21, 2023
Once every 3 months Expensive
By Deb
Redondo Beach, CA
Happy Customer
April 20, 2023
Bravecto has been working well for our Labrador. It was time to reorder and I discovered a better price here at Entirely Pets Pharmacy. They contacted our vet for a prescription and made the process very easy. I appreciate the attractive pricing and the great customer service!
By ttpp
April 18, 2023
Lowest price I could find. Fast shipping. Works for my dog!
By Jean
A must product
April 11, 2023
Great price, great item, a must for my fur baby. Thanks will order again.
By Sarah K.
Marlborough, MA
38lb Boston Terrier- Excellent Results!
April 11, 2023
My Boston Terrier never gets any ticks or fleas Ron her. This stuff works great. She is 7yrs old and no health concerns before or after using Bravecto.

Merchant Response:Hello Sarah, Your Boston Terrier looks absolutely adorable, thank you for the positive feedback! Sincerely, EntirelyPets Pharmacy
No pests on my dog whatsoever. Works perfectly! Haven
By Sarah K.
Marlborough, MA
65lb English Bulldog- 👍 Great Stuff
April 11, 2023
I‚€™ve used Bravecto 3mth chews since he was old enough. 3yrs now and Never have seen a tick on him, even after his jaunts in a field of ferns and tromping through the woods! No health issues, but he is extraordinarily healthy for an English Bulldog!

Merchant Response:Hello Sarah, That is great to hear, we're happy your and your pet continue to see results using the Bravecto, Your English Bulldog is beautiful! Sincerely, Jacqueline K.
Always better pricing here, with available discounts & virtual coupons via text. None I have experienced.
By Linda
Flea and tick prevention
April 1, 2023
Works best to kill fleas
By Nebears
Works for my dog
March 22, 2023
I like this product, just wish it wasnt so expensive. I am going to have to re-evaluate if it goes up much more, finances are tight.
Merchant Response:Hello Corrie, We are pleased to hear you enjoy the product, regarding the price our pharmacy tried its best to offer the best price, if you sign up for an email notification you will get notified with discount codes or specials on different items we have available. Sincerely, EntirelyPets Pharmacy
1 x every 90 days. Expensive Like most bugs have to bite b4 die Can make some animals sick
By Chelsea
Appreciate their dedication to providing fulfilling my order
March 18, 2023
They were prompt in reaching out to my vet to fulfill my order. Even followed up a second time and kept me informed every step along the way. They called my vet when faxes went unanswered. Customer service was very clear and helpful when I called about next steps because my vet wouldn‚€™t work with an online pharmacy. Eventually had to mail a handwritten script to their location.

Speedy and hassle free service, got the medicine within 2 weeks of this whole process.
By T
March 17, 2023
Love it! Easy, once every three months!
By Lady's M.
Temple City, California
My dog likes Bravecto.
March 16, 2023
My dog was on Bravecto at the Humane Society when we got her. So we have continued her on this and have had no problems.
By Tracy
Better than Chewy
March 13, 2023
It was so easy to place a new order! Entirely Pets contacted my vet and kept open lines of communication throughout the entire process. Great prices and fast, east shipping!
Merchant Response:Hello Tracy, Thank you for the positive feedback! Our pharmacy works hard to make sure all orders are approved and shipped in an appropriate time frame, we look forward to future feedback. Sincerely, EntirelyPets Pharmacy
By Meg
Florence, SC
Prompt service.
March 3, 2023
Always prompt!
Merchant Response:Hello Mary, Thank you for your feedback, we hope you continue to enjoy ordering with us in the future. Sincerely, EntirelyPets Pharmacy
I save a good bit of money.
United States of America
Bravecto Keeps our GSDs Flea & Tick Free!
February 22, 2023
Easy to use product given once to each dog every quarter. (We use the 3 month dose.) The dogs eat it like a treat and stay flea and tick free. Great price and fast contact with our Vet. Free shipping. We recommend this product for combatting fleas and ticks.
By Maxine
Athens, GA
No More Fleas
January 31, 2023
EntirelyPets filled my dog's prescription quickly and efficiently. I was able to take advantage of a reduction in price, and it arrived quicker than I expected. I will certainly continue to use this pharmacy.
By Laurie
Akron Ohio
Best Price
January 8, 2023
This a great product, and the price is the lowest I could find!!!
By NoWay
Must have item - better price than competitors - that simple ...
January 1, 2023
Still too expensive - like everything - makes it more likely we won't have pets in the future - simply can not afford to take care of them properly.
Cheaper than competition but still too expensive. Fairly easy to set up account and place order. Too expensive, still. Veterinarian was uncooperative and, the information provided back to me by EntirelyPetsPharmacy was vague.
By Cathy
Clarion, Pennsylvania
Bravecto flea and tick med
December 25, 2022
Easy to order, immediate contact with vet, and quick delivery.
Price and easy to order Shipping fee
By Loretta
Columbus, OH
Best Product Ever
December 14, 2022
I have used this not only for fleas and tick protection, but at times for dogs with Demodex. It is a great product for dogs with skin issues and is used to treat some. Price is great too.

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