Ondansetron is used in dogs and cats to treat a variety of conditions with the most common being vomiting, particularly chemotherapy associated-vomiting. It can also be used to treat sleep-apnea and pruritus (itching) in some pets.
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Ondansetron Inj 40mg/20ml (20 ml) (Manufacturer may vary)
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- Description
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- FAQ
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Description
Ondansetron is an antiemetic drug used to treat or prevent severe vomiting in dogs and cats. While the FDA has approved it only for use in humans, veterinarians may prescribe it in certain situations.
Key Features
- Treats vomiting (particularly chemotherapy associated-vomiting)
- May treat sleep apnea
- May treat pruritus in some pets
How It Works
Ondansetron is a drug that selectively inhibits serotonin 5HT3 receptors. 5HT3 receptors are located on vagal nerve terminals, enteric neurons in the GI tract, and centrally in the brain in a region called the chemoreceptor trigger zone.
Indications
Ondansetron is an antiemetic used for severe vomiting in dogs and cats. Ondansetron,metoclopramide, and maropitant are equally effective in reducing the frequency of vomiting in dogswith parvoviral enteritis. Ondansetron can be particularly effective for treating chemotherapy-associated vomiting. A study in cats found that ondansetron 0.22 mg/kg IM administered withdexmedetomidine and buprenorphine (in the same syringe) reduced the incidence (≈33%) and severityof nausea and vomiting when compared to ondansetron given 30 minutes before dexmedetomidine andbuprenorphine (67%) or when ondansetron was not given (76%).
Directions
Consult with your veterinarian on recommended dosage
FAQ
Treats vomiting (particularly chemotherapy associated-vomiting) -May treat sleep apnea -May treat pruritus in some pets
Ondansetron is a drug that selectively inhibits serotonin 5HT3 receptors. 5HT3 receptors are located on vagal nerve terminals, enteric neurons in the GI tract, and centrally in the brain in a region called the chemoreceptor trigger zone.
This medication is not frequently used in veterinary medicine, but it appears to be well tolerated. Side effects such as constipation, sedation, extrapyramidal clinical signs (head shaking), arrhythmias and hypotension are possible. If you notice anything unusual, contact your veterinarian.
Keep away from children and animals. Ondansetron should not be used in animals with known hypersensitivity or allergy to the drug.
Contact your nearest emergency animal hospital
