Vetoryl 5 mg, 30 Capsules | Free Shipping | EntirelyPets Rx
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Vetoryl (Trilostane) 5 mg (30 Caps)

Item# IWM060584
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  • Description
  • Ingredients
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  • FAQ
  • Reviews


Vetoryl Capsules 5 mg are an FDA-Approved solution used to treat dogs with pituitary-dependent and adrenocortical tumor-dependent hyperadrenocorticism. Hyperadrenocorticism is also commonly known as Cushing's Disease.

Key Benefits

  • Improvement seen within several weeks
  • Available in 5 mg, 10 mg, 30 mg, 60 mg, or 120 mg capsules (based on weight)
  • FDA-Approved

How It Works

Vetoryl uses a chemical (Trilostane) that controls the adrenal gland's excess production of cortisol, a hormone released into the bloodstream during times of stress.


Do not give this medication to dogs with kidney or liver disease. Vetoryl capsules should not be given to dogs taking certain medications or dogs that are pregnant. Speak with your veterinarian about all medications your dog is taking, including over-the-counter medicines.

prescription required symbol

NDC 17033-105-30

NADA 141-291


Active IngredientAmount
Trilostane5 mg


Give this medication exactly as directed by your veterinarian.Wash your hands after use. Do not handle the capsules if you are pregnant or trying to become pregnant. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you.

View Vetoryl package insert for more information.

Dosage & Administration

  • Administer 1 capsule of appropriate concentration for your dog's weight (see table below)
  • Give this medication with food
  • Concentrations may be mixed to achieve the correct dose for your dog

Quick Tips

  • Vetoryl is used to treat dogs with hyperadrenocorticism, also known as Cushing's Disease.
  • Vetoryl capsules should be given with food.
  • Do not open capsules and do not attempt to split or divide capsule.

Dosage Table

3.8 to 10 lbsOne 10 mg capsule daily
10 to 22 lbsOne 30 mg capsule daily
22 to 44 lbsOne 60 mg capsule daily
44 to 88 lbsOne 120 mg capsule daily
88 to 132 lbsOne 120 mg capsule of 120 mg and one 60 mg capsule daily (180 mg total)
Over 132 lbsAdminister the appropriate amount of capsules based on dog's weight. Speak with your veterinarian to help you determine the correct dosage for your dog.

Storage Directions

Store at room temperature 25°C (77°F) with excursions between 15°- 30°C (59°- 86°F) permitted. Keep out of reach of children and pets.


The use of Vetoryl Capsules is contraindicated in dogs that have demonstrated hypersensitivity to trilostane. Do not use Vetoryl Capsules in animals with primary hepatic disease or renal insufficiency . Do not use in pregnant dogs. Studies conducted with trilostane in laboratory animals have shown teratogenic effects and early pregnancy loss.

Possible Side Effects

If any of the following serious side effects occur, stop giving Vetoryl and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips, tongue or face; hives), severe depression, bloody diarrhea, collapse, or other severe reactions. Other less serious side effects such as unexpected decrease in appetite, vomiting, diarrhea, and lethargy may occur. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your dog.


Give the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not give a double dose of the medication.
Seek emergency veterinary medical treatment. Symptoms of Vetoryl overdose may include lethargy, weakness, vomiting, or collapse.
Do not give Vetoryl to dogs with kidney or liver disease. Do not give to pregnant or nursing dogs or dogs intended for breeding. Do not touch Vetoryl capsules if you are pregnant or trying to become pregnant.
Before giving Vetoryl tell your veterinarian if your pet is also taking ACE inhibitors such as enalapril, potassium sparing diuretics such as spironolactone, ketoconazole, or potassium supplements. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines or nutritional supplements.
Tell your veterinarian if your pet has kidney or liver disease. Tell your veterinarian about any other medical problems or allergies your dog has now or has had in the past. Tell your veterinarian about any medications your dog is taking including over the counter products and nutritional supplements. Tell your veterinarian if your pet is pregnant, nursing, or if you plan to breed your dog.


Review Summary
6 Reviews
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100% Recommend this product (6 of 6 responses)
By updateCategoJimryParent
Raleigh, NC
The medicine is fine; Entirely Pets Pharmacy
September 4, 2020
This medicine seems to really help with my dog's cushing's symptoms. I placed it on auto ship (or whatever it is that Entirely Pets calls it to have it shipped to me every 30 days) and they had a "glitch" in the system and didn't ship it. My dog went over a week without her medicine and her symptoms came roaring back. It was uncomfortable for everyone. There's no way for me to check if it's setup for autoship or not so now the onus is on me to call them to make sure it's shipped on time.
By A C.
Westlake Village, CA
Without Vetoryl my dog would be dead. That says it all.
October 6, 2019
My dog Bella has Cushing's disease, so without Vetoryl, Bella would be dead. I think that says it all.

However, since she does take Vetoryl twice a day, she is happy, active, playful and is totally fine, except for some weakness in her right leg from a spinal problem.

I am grateful beyond words to Dechra, who makes Vetoryl.
  • Keeps my dog alive.
  • Vetoryl isn't free.
By Susan B.
Nine Mile Falls WA
October 11, 2018
Get product for my dog . Fast delivery
  • All good quality product
  • no cons
By sheree s.
easy to order
August 30, 2018
Good value and good service.
Merchant Response:Thank you for your kind words Sheree! Glad we are able to help!
By Bambi L.
Tucson, AZ
Cushings Disease
September 4, 2016
My 10 lb dog takes this am and pm. Amazing how well it works. Her blood work is back to normal
  • Instead of 10mg once a day 5mg twice a day impressed with how quickly the meds worked
  • Has to be taken with food. Other than treats it's hard to get my dog to eat something healthy at med time. Have had to get canned dog food
San Diego, Ca.
Fast response and delivery
August 4, 2016
I appreciate your promptness in contacting my vet, getting authorization for the medication and sending it to me.

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