Carprofen Caplets are a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce pain and inflammation (soreness) due to osteoarthritis and pain following surgery in dogs. Carprofen Caplets are a prescription drug for dogs. It is available as a caplet and is given to dogs by mouth.
Osteoarthritis (OA) is a painful condition caused by “wear and tear” of cartilage and other parts of the joints that may result in the following changes or signs in your dog:
Always provide Client Information Sheet with prescription. Carefully consider the potential benefits and risk of Carprofen Caplets and other treatment options before deciding to use Carprofen Caplets. Use the lowest effective dose for the shortest duration consistent with individual response. The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Caplets are scored, and dosage should be calculated in half-caplet increments.
Effectiveness: Confirmation of the effectiveness of carprofen for the relief of pain and inflammation associated with osteoarthritis, and for the control of postoperative pain associated with soft tissue and orthopedic surgeries was demonstrated in 5 placebo-controlled, masked studies examining the anti-inflammatory and analgesic effectiveness of carprofen caplets in various breeds of dogs.
Separate placebo-controlled, masked, multicenter field studies confirmed the anti-inflammatory and analgesic effectiveness of carprofen caplets when dosed at 2 mg/lb once daily or when divided and administered at 1 mg/lb twice daily. In these two field studies, dogs diagnosed with osteoarthritis showed statistically significant overall improvement based on lameness evaluations by the veterinarian and owner observations when administered carprofen at labeled doses.
Separate placebo-controlled, masked, multicenter field studies confirmed the effectiveness of carprofen caplets for the control of postoperative pain when dosed at 2 mg/lb once daily in various breeds of dogs. In these studies, dogs presented for ovariohysterectomy, cruciate repair, and aural surgeries were administered carprofen preoperatively and for a maximum of 3 days (soft tissue) or 4 days (orthopedic) postoperatively. In general, dogs administered carprofen showed statistically significant improvement in pain scores compared to controls.
All dogs should undergo a thorough history and physical examination before initiation of NSAID therapy. Appropriate laboratory tests to establish hematological and serum biochemical baseline data before, and periodically during, administration of any NSAID should be considered. Owners should be advised to observe for signs of potential drug toxicity (see information for Dog Owners, Adverse Reactions, Animal Safety, and Post-Approval Experience).
What kind of results can I expect when my dog is on Carprofen Caplets? While Carprofen Caplets is not a cure for osteoarthritis, it can relieve the pain and inflammation of OA and improve your dog's mobility.
Who should not take Carprofen Caplets? Your dog should not be given Carprofen Caplets if he/she:
Carprofen Caplets should be given to dogs only. Cats should not be given Carprofen Caplets. Call your veterinarian immediately if your cat receives Carprofen Caplets. People should not take Carprofen Caplets. Keep Carprofen Caplets and all medicines out of reach of children. Call your physician immediately if you accidentally take Carprofen Caplets.
How to give Carprofen Caplets to your dog. Carprofen Caplets should be given according to your veterinarian's instructions. Your veterinarian will tell you what amount of Carprofen Caplets are right for your dog and for how long it should be given. Carprofen Caplets should be given by mouth and may be given with or without food.
What to tell/ask your veterinarian before giving Carprofen Caplets.
What are the possible side effects that may occur in my dog during Carprofen Caplets therapy? Carprofen Caplets, like other drugs, may cause some side effects. Serious but rare side effects have been reported in dogs taking NSAIDs, including carprofen. Serious side effects can occur with or without warning and in rare situations result in death.
The most common NSAID-related side effects generally involve the stomach (such as bleeding ulcers), and liver or kidney problems. Look for the following side effects that can indicate your dog may be having a problem with Carprofen Caplets or may have another medical problem:
It is important to stop therapy and contact your veterinarian immediately if you think your dog has a medical problem or side effect from Carprofen Caplets therapy. If you have additional questions about possible side effects, talk to your veterinarian.
Can Carprofen Caplets be given with other medicines? Carprofen Caplets should not be given with other NSAIDs (for example, aspirin, deracoxib, etodolac, firocoxib, meloxicam, tepoxalin) or steroids (for example, cortisone, dexamethasone, prednisone, triamcinolone). Tell your veterinarian about all medicines you have given your dog in the past, and any medicines that you are planning to give with Carprofen Caplets. This should include other medicines that you can get without a prescription. Your veterinarian may want to check that all of your dog’s medicines can be given together.
What do I do in case my dog eats more than the prescribed amount of Carprofen Caplets? Contact your veterinarian immediately if your dog eats more than the prescribed amount of Carprofen Caplets.