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Heartgard for Dogs & Puppies

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Heartgard Chewables for Dogs Powerful protection from heartworm. Tasty Heartgard chewables for dogs prevent heartworm infection for a full month.

  • Prevents heartworm disease
  • Prevents development of adult stage heartworms
  • Recommended for year-round use
  • Beef flavor chewable

Prescription Heartgard chewables contain the highly effective active ingredient Ivermectin that prevents heartworm infection by killing the parasite at the larval stage. By giving your dog a chewable once a month on the same day you will have peace of mind knowing that your dog is protected from dangerous heartworm.

Key Benefits

  • Highly effective in preventing heartworms
  • A convenient and tasty chewable for easy administration
  • Delicious beef flavor that most dogs will eat

How It Works

Heartgard prevents heartworm disease by eliminating the tissue stage of heartworm larvae for a month after infection.

Prescription Required

NADA 140-866


Dosage & Administration

Give Heartgard exactly as directed by the veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Heartgard chewable tablets must be chewed. They should not be swallowed whole. Use with caution, Collies and other herding dog breeds have been known to have adverse reactions to ivermectin administered at elevated dose levels. Heartworm testing should be performed before the start of prevention therapy. If the animal is off Heartgard Chewables for 6 months or less, start the medication and test after 6 months since microfilaria that takes 6 months to mature will result in a positive test result. Store Heartgard chewable at room temperature. Do not remove the chew from its wrapper until ready to give the medicine. Keep this medication away from children and pets. Also, Dog Heartgard Chewables has shown a wide margin of safety at the recommended dose level in dogs including pregnant or breeding bitches, stud dogs and puppies aged 6 or more weeks.

Quick Tips

  • Dog Heartgard Chewables are a once-a-month chewable tablet available by prescription for the prevention of heartworm disease in dogs.
  • It is recommended by the American Heartworm Society that heartworm prevention be given year-round.
  • Do not remove the chew from its wrapper until ready to give.
  • Dog Heartgard Chewables must be chewed. They should not be swallowed whole. For dogs that normally swallow whole, the chewable tablet can be broken into pieces.
  • Do not give a double dose of the medication.

Dosage Table

Weight Dosage
Dogs Up to 25 lbs Give 1 chewable tablet (68mcg-blue box) once a month
26-50 lbs Give 1 chewable tablet (136mcg-green box) once a month
51-100 lbs Give 1 chewable tablet (272mcg-brown box) once a month
Over 100 lbs Give the appropriate combination of chewable tablets once a month

Storage Directions

Store this product at room temperature. Keep out of reach of children.


Can cause sensitivities in herding dog breeds. It is important that you give your pet this preventative every month. If you miss more than two monthly doses, we recommend calling your vet before continuing the medication. Also, note that side effects are rare at the recommended heartworm prevention dose. Higher doses in dogs may cause tremors, dilated pupils, loss of body weight, and death. Side effects in cats include agitation, loss of appetite, staggering, dilated pupils, tremors, blindness and disorientation.


What happens if I miss giving a dose?

Give the missed dose as soon as you remember. Do not give a double dose of the medication.

What happens if I overdose the pet?

Seek emergency veterinary medical treatment. Symptoms of overdose may include vomiting, diarrhea and lack of coordination in dogs.

What should I avoid while giving Heartgard Chewables?

To help with compliance and not missing a monthly dose, use the handy red heart reminder stickers included with the medication.

What are the possible side effects of Heartgard Chewables?

Side effects of Heartgard are rare at the recommended heartworm prevention dose. Higher doses in dogs may cause tremors, dilated pupils, and loss of body weight and death.

What other drugs will affect Heartgard Chewables?

Do not give Heartgard to your pet if already taking another heartworm medication.


Review Summary
12 Reviews
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100% Recommend this product (12 of 12 responses)
By Kelly
Lindenhurst, IL
Prefer this over the new competition
October 23, 2019
I've been using Heartguard for almost 30 years on all my pets. My vet recently recommended Iverhart Plus as a second option regarding heartworm prevention. I agreed to try it and came right back to Heartguard. The dogs much prefer the chewable than the tablet Iverhart has.
Thanks Heartguard, for sticking with what works.
ProsDogs like the taste, I like the ease.
By Gail G.
Best company!
September 19, 2019
This medication was the most reasonable and came quickly!
By Susan
Heartgard Reg.
November 7, 2018
Perfect product for my dog.
Merchant Response:Hi Susan, My dog uses the Heartgard as well and he loves it. The chew makes it super easy to take for them.
ProsHe does not get sick with his one.
By Richard
Frisco, TX
January 27, 2018
Same product that you would buy from your vet. But you will save quite a bit.
By Pat
Very easy to use
September 15, 2017
Great. Items came quickly and communicated
At each step if order.
Merchant Response:Thank you for the feedback Pat, glad we could help!
By Dan K.
Mechanicsburg, PA
June 9, 2017
My dogs think this medication is a treat. They look forward to getting it monthly. My local vet does not carry this product. Many thanks to Entirely Pets Pharmacy.
By T
Springfield, MO
July 23, 2016
Every order I place with Entirely Pets I receive quality products, excellent costumer service and great delivery. I order most of my dogs supplies from this company. I love Entirely Pets and will continue to place my orders here.
By Susan
Los California
Important Protection at a Good Price!
June 8, 2016
We have been giving Heartgard to our dogs for decades. The vet recommended them and the protection from heart worms is important. All of our dogs have taken the pill without any hesitation and with no side effects. The price is better than the vet's or Costco's.
By Philica
Mountain Grove, MO
August 14, 2015
I am just pleased with the ease of medicating my pets with this product. They love the taste and their heartworm test is negative every year.
By Barbara
No heartworms.
June 21, 2015
Best to keep our dog safe from heartworms.
By Sally J.
A once again satisfied returning customer
May 17, 2015
Entirely Pets is a great source for conventional meds as well as medication supplements for pets. Their prices are competitive if not less then other online pet pharmacies and their service is very efficient. The pet meds I ordered were @ my house in just a few days. I have been getting my little dogs Hearguard from another online pharmacy but they were not able to beat Entirely Pets prices and b/c I use too order meds from Entirely Pets, and was always satisfied, I decided to place my order once again w/ them. Thanks Entirely Pets for your consistent online ordering made easy.
By Philica
Mountain Grove, MO
It was great.
April 10, 2015
I have used this for the life of both my pets. As per their yearly tests, they have both been Heartworm free every year. This is a very good product and I would not use any other. Entirely Pets Pharmacy has made receiving this product very easy and cost efficient.

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