Heartgard Chewable Tablets for Cats | EntirelyPets Pharmacy
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Heartgard for Cats & Kittens

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Heartgard Chewables fprevents feline heartworm disease in cats and kittens. The active ingredient in this product is ivermectin. Ivermectin kills heartworms in the larval stage. It also helps to eliminate intestinal parasites, such as hookworms. Ivermectin works by interfering with the nerve transmission of the immature heartworms and hookworms.

Key Benefits

  • Highly effective in preventing heartworms
  • Removes and controls adult and immature hookworms
  • A convenient and tasty chewable for easy administration
  • Delicious beef flavor that most cats will eat


For use in cats to prevent feline heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days) after infection, and for the removal and control of adult and immature hookworms (Ancylostoma tubaeforme and A. braziliense).

How it works

Heartgard Chewables for Cats prevent heartworm disease by eliminating the tissue stage of heartworm larvae for a month after infection.


Heartgard Chewables for Cats Red (for Cats 1-5 lbs):
Active Ingredient Amount
Ivermectin 55 mcg
Heartgard Chewables for Cats Purple (for Cats 5-15 lbs):
Active Ingredient Amount
Ivermectin 165 mcg


HEARTGARD for Cats should be administered orally at monthly intervals at the recommended minimum dose level of 24 mcg of ivermectin per kg (10.9 mcg/lb) of body weight. The recommended dosage schedule for prevention of feline heartworm disease and control of hookworm is as follows:

Cat Weight Heartgard for Cats Chewables per Month Ivermectin content
Up to 5 lb 1 55 mcg
5 to 15 lb 1 165 mcg

For cats over 15 lb, use the appropriate combination of chewables.

HEARTGARD for Cats is recommended for use in cats 6 weeks of age and older.


Remove only one chewable at a time from the foilbacked blister card. Return the card with the remaining chewables to its box to protect the product from light. HEARTGARD for Cats can be offered to the cat by hand or may be added to a small amount of cat food. If manual dosing is required, the chewable should be broken into pieces for administration. Food should be routinely available during the day of treatment administration. If cats are fasted, or if the chewable is not broken into pieces for manual dosing, then reduced absorption may result. A relationship between reduced absorption and reduced efficacy has not been established.

Care should be taken to see that the cat consumes the complete dose. Treated animals should be observed for a few minutes after administration to ensure that part of the dose is not lost or rejected. If it is suspected that any of the dose has been lost, redosing with a new chewable is recommended. Fragments of chewables have occasionally been observed in the feces of some cats; efficacy of the product was not adversely affected.

HEARTGARD for Cats should be given at monthly intervals when mosquitoes potentially carrying infective heartworm larvae are active. The initial dose must be given within a month (30 days) after the cat's first exposure to mosquitoes. The final dose must be given within a month (30 days) after the cat's last exposure to mosquitoes. For optimal performance, HEARTGARD for Cats must be given once a month on or about the same date. If treatment is delayed, whether by a few days or many, immediate treatment with HEARTGARD for Cats and resumption of the recommended dosing regimen will minimize the opportunity for development of adult heartworm.

It is recommended that cats should be tested for existing heartworm infection prior to starting treatment with HEARTGARD for Cats. Cats already infected with adult heartworms can be given HEARTGARD for Cats monthly to prevent further infections.

Monthly treatment with HEARTGARD® (ivermectin) for Cats also provides effective removal and control of adult and immature hookworms (A. tubaeforme and A. braziliense).


In the clinical studies involving more than 3000 doses of HEARTGARD for Cats, observations reported within 24 hours of treatment included vomition in ? 0.3% and diarrhea in ? 0.2% of the doses administered. There were no statistical differences between HEARTGARD for Cats and the product vehicle (control) for these observations.

A wide margin of safety was demonstrated in clinical trials at the recommended dose level in cats and kittens 6 weeks of age and older and in laboratory studies in cats with circulating microfilariae of D. immitis. A wide margin of safety has also been demonstrated at 3 times the recommended dose in pregnant or breeding queens and breeding toms. No adverse effects were observed in either male or female cats or their offspring in breeding studies. A 30-fold safety margin over the minimum recommended dosage was established in a single dose tolerance study. In growing kittens dosed monthly for 8 consecutive doses, one cat given 5 times the market dose vomited and a second cat in this group experienced diarrhea within 24 hours of the initial treatment. In clinical trials, many commonly used flea control products, anthelmintics, vaccines, antibiotics and steroid preparations were administered with HEARTGARD for Cats without incident.

Keep this and all drugs out of the reach of children. In case of ingestion by humans, clients should be advised to contact a physician immediately.


HEARTGARD Chewables for Cats are stable for 3 years when stored below 77°F (25°C) and protected from light. Store at controlled room temperature of 68°F-77°F (20°C-25°C). Excursions between 59°F-86°F (15°C-30°C) are permitted.


  • Keep out of reach of children and pets.
  • It is important that you give your pet this preventative every month.
  • If you miss than two monthly doses, we recommend calling your vet before continuing the medication.
  • Also, note that side effects are rare at the recommended heartworm prevention dose.
  • Side effects in cats include agitation, loss of appetite, staggering, dilated pupils, tremors, blindness and disorientation.

Possible side effects:

Adverse reactions and serious side effects are rare, however, they can occur. In the case of a more serious side reaction, seek immediate veterinary attention. Serious reactions include vomiting, depression/lethargy, diarrhea, shaking, seizures, uncontrollable body movements, or unusual salivation.


Heartworm disease in cats (dirofilariasis) is a serious and potentially fatal disease. Heartworms spend their adult lives in the pulmonary arteries. The adult worms can cause lasting damage to the heart, lungs and arteries.
Heartworms are transmitted from one cat to another by mosquitoes, which pick up tiny immature heartworms, called microfilariae, when they bite an infected cat. Larvae develop and are then transmitted to another cat when that cat is bitten by the infected mosquito.
All cats are at risk for heartworm disease, no matter where they live heartworms don't discriminate based on geography. In the past, heartworm disease in the United States was primarily limited to the South and Southeast regions. However, it is now found in all 50 states, in Canada, and is spreading to new areas each year. The American Heartworm Society notes that uncared-for cats and certain wildlife can be carriers of heartworms. Mosquitoes blown great distances by the wind and the transportation of infected pets to different geographic locations can all contribute to the spread of heartworm disease.
Signs of heartworm disease can be subtle and difficult to detect until its later stages. As the disease progresses, signs begin to appear. Contact your veterinarian immediately if you notice coughing, difficulty breathing, sluggishness and less energy for exercise in your cat. Adult heartworms cause serious harm to your cat's heart, lungs and certain internal organs. Left untreated, heartworm disease can result in loss of consciousness and death.
The most common method for heartworm testing is for a veterinarian to collect a small blood sample from a cat and evaluate the sample using a specialized test kit to detect the presence of adult heartworms.
Pet owners can use Heartgard (ivermectin) to help prevent heartworm disease. Heartgard kills tissue larval stages of heartworms and helps prevent them from developing into adults and causing heartworm disease. In an unprotected cat, heartworm larvae mature into adults and ultimately migrate to the arteries of the lungs.
Monthly use of Heartgard is essential because it cannot be determined with certainty when the threat of mosquitoes has passed. Talk to your veterinarian for dose and regimen recommendations.
Although it is possible to treat heartworm disease if a cat becomes infected, it is difficult, expensive and risky, particularly in cats that have begun to exhibit clinical signs of infection.
There are treatment options available to kill adult heartworms in cats that have become infected. Treating cats with heartworm disease starts with a thorough physical examination by the veterinarian. The veterinarian will then discuss treatment options with you. Typically, the cat is hospitalized during the treatment period. Because there is a risk of blood clots or worm debris blocking blood vessels from adult heartworm treatment, the cat must then remain quiet in close confinement for another 4 to 6 weeks after treatment. A second round of treatment may be required for some cats. The veterinarian may also give your cat a treatment to rid it of the immature larvae that are circulating through the blood stream.
Heartgard is safe and effective in any breed of cat when used as directed.
No, the way cats become infected is via a bite from a mosquito that is carrying heartworm larvae.
No. kittens that are nursing may become infected. Heartgard can be used in kittens as young as 6 weeks of age and kittens benefit from the ability of Heartgard to treat and control roundworms and hookworms.


Review Summary
3 Reviews
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100% Recommend this product (3 of 3 responses)
By William
El Paso, TX
Same as from vet but $20 less expensive
August 24, 2019
Exact product that the veterinarians dispense...
By Dana
Heartgard cats
February 21, 2019
Best prices and quick delivery.

By Ginger
San Antonio, TX
Easy to administer
October 7, 2015
This product is easy to administer. Our cats are eager to take it, experiencing it more as a treat than as necessary medicine.

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