Cytopoint | Description & Info | EntirelyPets Rx
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Due to Cytopoint's need to be kept between 2 - 8 C, it must be shipped Express 1-2 days. Express shipping fees are an additional $29.95. Someone should be present to sign for and receive the order because of its sensitive condition. For more shipping info click here.


Cytopoint is prescribed for dogs with atopic dermatitis to help reduce scratching, chewing, licking and biting at the skin. When the itch is controlled, the damaged skin can heal, so that you and your dog have a chance to enjoy the fun things in life again.

It is an innovative new therapy that targets itch at its source to help relieve the signs of atopic dermatitis in dogs for a month or longer with a single injection.

Medical Use

Cytopoint aids in the reduction of clinical signs associated with atopic dermatitis in dogs.

Key Benefits

  • Helps control itch for 4-8 weeks.
  • Works after a single injection.

How It Works

Cytopoint remains in circulation for several weeks. It exerts a therapeutic effect by binding to and neutralizing soluble IL-31, thus inhibiting pruritus and reducing skin lesions. Like other naturally-occurring antibodies and antibody-antigen complexes, elimination is via normal protein degradation pathways.


  1. The product does not have a preservative. Each vial is for single use only, and should be discarded after puncture.
  2. This product is intended for subcutaneous use only.
  3. Store upright at 2 - 8 C. Prolonged exposure to higher temperatures and/or direct sunlight may adversely affect potency. Do not freeze.
  4. Use entire contents when first opened.
  5. Sterilized syringes and needles should be used to administer this product. Do notsterilize with chemicals because traces of disinfectant may inactivate the product.
  6. This product has not been tested in pregnant, lactating or breeding animals.

For use by, or under the supervision of, a veterinarian.


Cytopoint is available in 1-mL vials in four concentrations (10, 20, 30 or 40 mg). Administer Cytopoint at a minimum dose of 0.9 mg/lb (2 mg/kg) body weight. For convenience, the dosing tables below may be used as a guideline. Repeat administration every 4-8 weeks as needed in individual patients.

The product does not contain a preservative. Each vial is for single use only, and should be discarded after puncture.

View Cytopoint Package Information

Dogs weighing < 5.0 lb (< 2.3 kg)

Aseptically withdraw 0.09 mL/lb (0.2 mL/kg) from a single, 10-mg (Sky) vial and administer subcutaneously (under the skin). Discard any remaining product.

Dogs weighing 5.0 - 40 lb (2.3 - 18.1 kg)

Aseptically withdraw the full volume of the appropriate vial according to the dosage table below and administer subcutaneously (under the skin).

Dog Body Weight (Pounds)Dog Body Weight (Kilograms)Presentation
10 mg (Sky)20 mg (Plum)30 mg (Blush)40 mg (Navy)
5.0 - 102.3 - 4.51 vial
10.1 - 204.6 - 9.11 vial
20.1 - 309.2 - 13.61 vial
30.1 - 4013.7 - 18.11 vial

Dogs weighing > 40 lb (18.1 kg)

A single dose requires a combination of vials, as outlined in the table below. Prior to administration, collect the number of vials indicated under each presentation according to the dogs body weight.

Aseptically draw the full volume from each vial into one syringe and administer subcutaneously (under the skin) as a single injection.

Dog Body Weight (Pounds)Dog Body Weight (Kilograms)Presentation
10 mg (Sky)20 mg (Plum)30 mg (Blush)40 mg (Navy)
40.1 - 5018.2 - 22.71 vial +1 vial
50.1 - 6022.8 - 27.21 vial +1 vial
60.1 - 7027.3 - 31.71 vial +1 vial
70.1 - 8031.8 - 36.32 vials
80.1 - 9036.4 - 40.81 vial +2 vials
90.1 - 10040.9 - 45.41 vial +2 vials
100.1 - 11045.5 - 49.91 vial +2 vials
110.1 - 12050.0 - 54.43 vials
120.1 - 13054.5 - 59.01 vial +3 vials
130.1 - 14059.1 - 63.51 vial +3 vials
140.1 - 15063.6 - 68.01 vial +3 vials
150.1 - 16068.1 - 72.64 vials
160.1 - 17072.7 - 77.11 vial +4 vials
170.1 - 18077.2 - 81.61 vial +4 vials
180.1 - 19081.7 - 86.21 vial +4 vials
190.1 - 20086.3 - 90.75 vials


Just one Cytopoint injection starts controlling allergic itch within one day and provides relief that lasts for 4 to 8 weeks. That means your dog may be able to go as long as 8 weeks between injections.
Yes. It is safe for dogs of all ages.
It can also be used in dogs on many other medications or dogs with other diseases. As always, be sure to tell your veterinarian about all the medications your dog is taking.
Your veterinarian may schedule a progress exam four weeks after the first injection. But, its dependent on your dogs individual needs. So, please consult your veterinarian.


Review Summary
4 Reviews
75% (3)
0% (0)
0% (0)
0% (0)
25% (1)
75% Recommend this product (3 of 4 responses)
By Han
portland, oregon
doesnt work
October 20, 2020
Vet gave our doodle 40 mg shot (or supposedly did) and NO EFFECT, still itching biting at self. wouldnt give apoquel which worked in the past within 4 hours. now i have to fight witht the vet clinic to get some meds that actually work. Injection 97$ total bill 198$ , dog still scratching. arrgh
Merchant Response:We are sorry to hear about your frustration Han, give us a call. We may have some solutions for the itching problem.
Consits like he got no treatment
By Badmiyagi s.
Peoria, AZ.
Sir Percy/Lord Percy had a royal itch!
August 21, 2019
Percy our Kack Russell/Chi mix has had an allergic itch for some time. The best thing we've tried are the Cytopoint injections. They last about 3 mos. which is pretty good and a great relief for the lil 'Hund', lol! Taking him back for the second installment.
By Jan
Stephenville, Texas
Itching stopped within 20 minutes of adminstration
March 26, 2019
My dog had been itching CONSTANTLY for days. The vet said that the shot would be effective
within 24 hours. By the time we drove home from the vet, my dog was no longer scratching.

ProsVery effective allergy relief for my dog
Consexpensive to treat dog every 4 weeks.
By Sharyn D.
St. Louis, Mo
My dogs reaction to medicine.
February 18, 2019
Caution up front in giving the shot. This medicine burns going in and last about 1 minute. So your dogs will probably react to it mine did. My vet help me with the first shot since I've never given one before, but forgot to tell me it burns going in. Too a few days for the medicine to get thur her system. This is the first time in over a year that I've not seen her try to scratch herself to death. It WORKS and I'm so happy for both of us, especially for her. Great product thankful that it's in my pocket range that I can get it for her and my vet works with me on the script instead getting it himself and overcharging me for it. Thanks

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