Megestrol is a synthetic chemical similar to the female hormone progesterone. Megestrol is a prescription medication FDA approved for use in dogs. Megestrol is available as 20mg scored tablets. Megestrol is used to postpone estrus (female heat cycle) and to alleviate false pregnancy. When used to postpone estrus, the dose and duration of treatment depends on the stage of the cycle when therapy is begun. When used to treat false pregnancy, the usual dose is 1mg/pound given once a day for 8 days. Megestrol may also be used for purposes other than those listed in this medication guide.
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Description
Megestrol is an oral prescription tablet used in female dogs to help alleviate false pregnancies and help regulate female heat cycles. Megestrol is a synthetic chemical similar to the female hormone progesterone.
Key Features
- Easy to administer
- FDA approved for use in dogs
How It Works
Megestrol is a female hormone that through its actions regulates the female heat cycle and can be used to alleviate false pregnancy.
Indications
Megestrol acetate tablets are indicated for the palliative treatment of advanced carcinoma of the breast or endometrium (i.e., recurrent, inoperable, or metastatic disease). It should not be used in lieu of currently accepted procedures such as surgery, radiation, or chemotherapy.
Directions
- Megestrol is a prescription medication used to postpone the female heat cycle (estrus) and to treat false pregnancy in dogs.
- Megestrol should not be given to dogs prior to or during their first estrus cycle, or to pregnant dogs.
- Megestrol is a synthetic chemical similar to the female hormone progesterone.
- Megestrol is for use in dogs only. Do not give to cats.
- Allow pet to drink plenty of water.
Tip: Megestrol tablets may be given whole or crushed and mixed in food.
| Megestrol Dosage for Dogs | |
|---|---|
| Weight | Dosage |
| All weights | When used to postpone estrus, the dose and duration of treatments depends on the stage of the cycle when therapy is begun. When used to treat false pregnancy, the usual dose is 1mg/lb of pet's body weight given once a day for 8 days |
Cautions:
Megestrol should not be used in pregnant animals. Tell your veterinarian if your pet is being given insulin. Megestrol may decrease the effect of insulin and your pet's blood sugar may increase. Also contact your veterinarian if your pet experiences increased thirst or urination, depression, mammary gland enlargement, temperament changes, vaginal discharge, vomiting, or yellow gums while being treated with Megestrol. Other drugs may also interact with Megestrol, so talk to your veterinarian or pharmacist before using any prescription or over-the-counter medications.
Precautions:
Megestrol should not be given to dogs prior to or during their first estrus cycle, or to pregnant dogs. Megestrol is for use in dogs only. Do not give to cats. Allow pet to drink plenty of water while taking Megestrol.
Possible Side Effects
Weight gain is a frequent side effect of megestrol and is often due to increased appetite and is not necessarily associated with fluid retention. Other possible side effects may also occur including heart failure, nausea and vomiting, edema, breakthrough menstrual bleeding, dyspnea, tumor flare (with or without hypercalcemia), hyperglycemia, glucose intolerance, alopecia, hypertension, carpal tunnel syndrome, mood changes, hot flashes, malaise, asthenia, lethargy, sweating and rash.
Storage:
Store at or below 77°F.
FAQ
Tell your veterinarian if your pet has diabetes or a history of blood clots, Addison's disease, uterine disease or congestive heart failure. Tell your veterinarian if your pet is pregnant or if your pet is lactating.
Notify your veterinarian if your pet develops any side effects while taking megestrol.
Give this megestrol exactly as directed by your veterinarian. If you do not understand the directions, ask your pharmacist or veterinarian to explain them to you. Allow pet to drink plenty of water. Megestrol tablets may be given whole or crushed and mixed in food. Store megestrol at room temperature, away from moisture and heat.
There are no restrictions on food or activity during treatment with megestrol unless your veterinarian directs otherwise. Do not give megestrol to pregnant dogs or dogs with mammary tumors. Megestrol should not be given for more than two consecutive treatments.
If any of the following serious side effects occur, stop giving megestrol and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing, swelling of the lips, tongue, face, or hives), sudden severe headache; changes in vision; swelling in a leg. Other less serious side effects may also occur. Talk to your veterinarian if your pet experiences nausea or vomiting, dizziness, mild shortness of breath, weakness, headache, vaginal bleeding, sweating, and insomnia. Side effects other than those listed here may also occur. Talk to your veterinarian about any side effect that seems unusual or that is especially bothersome.
Tell your veterinarian if your pet is given insulin. Megestrol may decrease the effect of insulin and your pet's blood sugar may increase. Drugs other than those listed here may also interact with megestrol. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medications.
