DirectionsDosage & Administration:
Always provide Client Information Sheet with prescription. Carefully consider the potential benefits and risk of Carprieve and other treatment options before deciding to use Carprieve. Use the lowest effective dose for the shortest duration consistent with individual response. The recommended dosage for oral administration to dogs in 2 mg/lb of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight daily or divided and administered as 1 mg/lb tqice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Carprieve chewable tablets are scored and dosage should be calculated in half-tablet increments. Tablets can be halved by placing the tablet on a hard surface and pressing down on both sides of the score. These liver flavored Carprieve chewable tablets may be offered to the dog by hand or placed on food. If the dog does not willingly consume the tablets, they may be hand-administered (pilled) as with other oral tablet medications. Care should be taken to ensure that the dog consumes the complete dose.
Confirmation of the effectiveness of carprofen for the relief of pain and inflammation associated with osteoarthritis, and for the control of postoperative pain associated with soft tissue and orthopedic surgeries, was demonstrated in 5 placebo-controlled, masked studies examining the anti-inflammatory and analgesic effectiveness of carprofen caplets in various of dogs.
Separate placebo-controlled, masked, multicenter field studies confirmed the anti-inflammatory and analgesic effectiveness of carprofen caplets when dosed at 2 mg/lb once daily or when divided and administered at 1 mg/lb twice daily. In these 2 field studies, dogs diagnosed with osteoarthritis showed statistically significant overall improvement based on lameness evaluations by the veterinarian and owner observations when administered carprofen at labeled doses.
Separate palcebo-controlled, masked, multicenter-field studies confirmed the effectiveness of carprogen caplets for the control of postoperative pain when dosed at 2 mg/lb once daily in various breeds of dogs. In these studies, dogs presented for ovariohysterectomy, cruciate repair and aural surgeries were administered carprofen preoperatively and for a maximum of 3 days (soft tissue) or 4 days (orthopedic) postoperatively. In general, dogs administere carprofen showed statistically significant reduction in pain scores compared to controls.
What is Carprieve?
Carprieve is nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce pain and inflammation (soreness) due to osteoarthritis and pain following surgery in dogs. Carprieve is a prescription drug for dogs. It is available as a caplet and chewable tablet and is given to dogs by mouth.
Osteoarthritis (OA) is a painful condition caused by "weat and tear" of cartilage and other parts of the joints that may result in the following changes or signs in your dog:
Limping or lameness
Decreased activity or exercise (reluctance to stand, climb stairs, jump or run, or difficulty in performing these activities).
Stiffness or decreased movement of joints
To control surgical pain (e.g. for surgeries such as spays, ear procedures or orthopedic repairs) your veterinarian may administer Carprieve before the procedure and recommend that your dog be treated for several days after going home.
What kind of results can I expect when my dog is on Carprieve?
While Carprieve is not a cure for osteoarthritis, it can relieve the pain and inflammation of OA and improve your dog's mobility.
Response varies from dog to dog but can be quite dramatic.
In most dogs, improvement can be seen in a matter od days.
If Carprieve is discontinued or not given as directed, your dog's pain and inflammation may come back.
What should not take Carprieve?
Your dog should not be given Carprieve if he/she:
Has had an allergic reaction to carprofen, the active ingredient of Carprieve.
Has had an allergic reaction to aspirin or other NSAIDs (for example deracoxib, etodolac, firocoxib, meloxicam, phenylbutazone or tepoxalin) such as hives, facial swlling, or red or itchy skin.
Carprieve should be given to dogs only.
Cats should not be given Carprieve. Call your veterinarian immediately if your cat receives Carprieve. People should not take Carprieve. Keep Carprieve and all medicines out of reach of children. Call your physician immediately if you accidentally take Carprieve.
How to give Carprieve to your dog.
Carprieve should be given according to your veterinarian's instructions. Your veterinarian will tell you what amount of Carprieve is right for your dog and how long it should be given. Offer Carprieve chewable tablets to the dog by hand or plave in the dog's mouth. If the dog does not willingly consume the tablet, hand-administer (pill). Carprieve may be given with or without food.
What to tell/ask your veterinarian before giving Carprieve.
Talk to your veterinarian about:
The signs of OA you have observed (for example limping, stiffness).
The importance of weight control and exercise in the management of OA.
What tests might be done before Carprieve is prescribed
How often your dog may need to be examined by your veterinarian.
The risks and benefits of using Carprieve
Tell your veterinarian if your dog has ever had the following medical problems:
Experienced side effects from Carprieve or other NSAIDs such as aspirin
Digestive upset (vomiting and/or diarrhea)
A bleeding disorder (for example, Von Willebrand's disease)
Tell your veterinarian about:
Any other medical problems or allergies that your dog has now or has had.
All medicines that your are giving your dog or plan to give your dog, including those you can get without a prescription.
Tell your veterinatian if your dog is:
Pregnant, nursing or if you plan to breed your dog.
What are the possible side effects that may occur in dog during Carprieve therapy?
Carprieve, like other drugs, may cause some side effects. Serious but rare side effects have been reported in dogs taking NSAIDs, including Carprieve. Serious side effects can occur with or without warning and in rare situations result in death.
The most common NSAID-related side effects generally involve the sotmach (such as bleeding ulcers), and liver or kidney problems. Look for the following side effects that can indicate your dog may be having a problem with Carprieve or may have another medical problem:
Decrease or increase in appetite
Change in bowel movements (such as diarrhea, or black, tarry or bloddy stools)
Change in behavior (such as decreased or increased activity level, incoordiantion, seizure or affression)
Yellowing of gums, skin, or whites of the eyes (jaundice)
Change in drinking habits (frequency, amount consumed)
Change in urination habits (frequency, color, or smell)
Change in skin (redness, scabs, or scratching)
It is important to stop therapy and contact your veterinarian immediately if oyu think your dog has a medical problem or side effect from Carprieve therapy. If you have additional questions about possible side effects, talk to your veterinarian.
Can Carprieve be given with other medicines?
Carprieve should not be given with other NSAIDs (for example, aspirin, deracoxib, etodolac, firocoxib, meloxicam, tepoxalin) or steroids (for example, cortisone, dexamethasone, prednisone, triamcinolone).
Tell your veterinarian about all medicines you have given your dog in the past, and any medicines that you are planning to give with Carprieve. This should include other medicines that oyu can get without a prescription. Your veterinarian may want to check that all of your dog's medicines can be given together.
What do I do in case my dogs eats more than the prescribed amount of Carprieve?
Contact your veterinarian immediately if your dog eats more than the prescribed amount of Carprieve.
How to store Carprieve Chewable Tablets.
Carprieve Chewable Tablets are designed to taste good to animals.
Keep Carprieve Chewable Tablets in a secured storage area out of the reach of your dog and other pets.
If your dog ingests more than your veterinarian prescribed, or if your other pets take Carprieve Chewable Tablets, contact your veterinarian right away.